Korean Circ J.  2010 Nov;40(11):593-595. 10.4070/kcj.2010.40.11.593.

A Case of Pulmonary Arterial Hypertension Associated With Hyperthyroidism, Persistent After Euthyroidism Was Obtained

Affiliations
  • 1Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. kimyd@mail.donga.ac.kr

Abstract

Cardiovascular manifestations in hyperthyroidism occur frequently with various phenotypes. An association between hyperthyroidism and pulmonary arterial hypertension has been reported. In previously reported cases, the hemodynamic and symptomatic recovery of pulmonary arterial hypertension is usually concomitant with achievement of euthyroidism. We report a patient who had pulmonary arterial hypertension associated with Graves' disease, which persisted after euthyroidism was obtained.

Keyword

Pulmonary hypertension; Hyperthyroidism; Graves' disease

MeSH Terms

Achievement
Graves Disease
Hemodynamics
Humans
Hypertension
Hypertension, Pulmonary
Hyperthyroidism
Phenotype
Hypertension, Pulmonary

Figure

  • Fig. 1 Chest radiograph on admission shows mild cardiomegaly with prominent pulmonary conus.

  • Fig. 2 Transthoracic echocardiography showing pulmonary artery pressure before (A) and after (B) treatment of hyperthyroidism.


Reference

1. Klein I. Thyroid hormone and cardiovascular system. Am J Med. 1990. 88:631–637.
2. Marvisi M, Brianti M, Marani G, Del Borello R, Bortesi ML, Guariglia A. Hyperthyroidism and pulmonary hypertension. Respir Med. 2002. 96:215–220.
3. Armigliato M, Paolini R, Aggio S, et al. Hyperthyroidism as a cause of pulmonary arterial hypertension: a prospective study. Angiology. 2006. 57:600–606.
4. Chu JW, Kao PN, Faul JL, Doyle RL. High prevalence of autoimmune thyroid disease in pulmonary arterial hypertension. Chest. 2002. 122:1668–1673.
5. Nakchbandi IA, Wirth JA, Inzucchi SE. Pulmonary hypertension caused by Graves' thyrotoxicosis: normal pulmonary hemodynamics restored by (131)I treatment. Chest. 1999. 116:1483–1485.
6. Virani SS, Mendoza CE, Ferreira AC, de Marchena E. Graves' disease and pulmonary hypertension: report of 2 cases. Tex Heart Inst J. 2003. 30:314–315.
7. Marvisi M, Zambrelli P, Brianti M, Civardi G, Lampugnani R, Delsignore R. Pulmonary hypertension is frequent in hyperthyroidism and normalizes after therapy. Eur J Intern Med. 2006. 17:267–271.
8. Kang BD, Cho DK, Byun KH, Eun YM, Cho YH. Isolated pulmonary arterial hypertension: Janus' faces of hyperthyroidism. Korean Circ J. 2009. 39:168–170.
9. Hegazi MO, El Sayed A, El Ghoussein H. Pulmonary hypertension responding to hyperthyroidism treatment. Respirology. 2008. 13:923–925.
Full Text Links
  • KCJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr