J Korean Child Neurol Soc.  2004 Nov;12(2):229-234.

A Case of Basal Ganglia Infarct Associated with SLE

• Cheong HY
• Yoon HC
• Suh ES

Abstract

Systemic lupus erythematosus(SLE), a rheumatic disease of unknown causes, is characterized by autoantibodies directed against self-antigens, resulting in inflammatory damages to target organs including kidney, blood-forming cells, and central nervous system. The prevalence rates are higher in Native Americans, Asians, Latin Americans and black people. A female to male ratio of approximately 2 : 1 occurs before puberty, and 4 : 1 after puberty. Children of SLE most frequently present with fever, fatigue, arthralgia or arthritis, and rashes. The diagnosis is confirmed by clinical and also laboratory manifestations satisfying at least 4 out of 11 criteria. A central nervous system is not rarely involved in children of SLE with the prevalence rate of 23-44%. However, cerebral infarcts are not a common phenomenon and can be seen only for 6% of children with SLE. There have been no cases reported in Korea. This is why we present a case of basal ganglia infarct associated with SLE in a 19-month old girl. We report this case with a brief review of related literature.

Keyword

Systemic lupus erythematosus; Basal ganglia infarct; Cerebrovascular disease

MeSH Terms

Adolescent
Arthralgia
Arthritis
Asian Continental Ancestry Group
Autoantibodies
Autoantigens
Basal Ganglia*
Central Nervous System
Child
Diagnosis
Exanthema
Fatigue
Female
Fever
Humans
Indians, North American
Infant
Kidney
Korea
Lupus Erythematosus, Systemic
Male
Prevalence
Puberty
Rheumatic Diseases
Autoantibodies
Autoantigens