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Proteomic Analysis of Airway Epithelial Cell Autoantigens Associated with Bronchial Asthma: Target Protein Identification Using Cultured Cell Fractionation Method

  • KMID: 2234529
  • Korean J Asthma Allergy Clin Immunol.
  • 2008 Sep;28(3):192-198.
BACKGROUND: Involvement of the autoimmune mechanism has been suggested for the pathogenesis of bronchial asthma and several autoantigens which are associated with bronchial asthma have been identified. OBJECTIVE: To identify novel...
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The Role of B Cells in Transplantation and Immunopathic Diseases

Basten A

B cells, by virtue of their diverse roles in immune responses to foreign and self antigens, have become of increasing interest to the clinician as well as the basic immunologist....
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NETosis in Autoimmune Diseases

Sohn DH

Neutrophils are the major antimicrobial cells of the innate immune system, which are recruited rapidly to the sites of infection and provide the primary defense against pathogens. Recent evidence suggests...
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Potential Role of Bacterial Infection in Autoimmune Diseases: A New Aspect of Molecular Mimicry

Alam J, Kim YC, Choi Y

Molecular mimicry is an attractive mechanism for triggering autoimmunity. In this review, we explore the potential role of evolutionary conserved bacterial proteins in the production of autoantibodies with focus on...
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Frontal Fibrosing Alopecia with Partial Improvement after Systemic Steroid Administration and Topical Calcineur in Inhibitor Application

Lee SY, Kim JH, Ji JH, Lee WS

  • KMID: 1451594
  • Korean J Dermatol.
  • 2011 May;49(5):436-439.
Frontal fibrosing alopecia (FFA) is a rare subtype of cicatricial alopecia. It was first described in 1994 by Kossard as postmenopausal frontal fibrosing alopecia. Patients who suffer from FFA show...
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Analysis of Airway Epithelial Cell Autoantigens Recognized by IgG Autoantibodies from Patients with Severe Asthma and Chronic Obstructive Pulmonary Disease

  • KMID: 2346806
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Dec;29(4):249-255.
BACKGROUND: The presence of circulating autoantibodies to airway epithelial cells has been reported in patients with asthma and chronic obstructive pulmonary disease (COPD). OBJECTIVE: To evaluate the possibility of a common...
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A case of Myasthenia Gravis associated with Premature ovarian failure and thyroid autoanibodies

Ham DS, Chang SH, Youn YC, Kim WJ, Kwon OS, Park HM, Kim DE, Lee KW

  • KMID: 2342490
  • J Korean Neurol Assoc.
  • 1995 Jun;13(2):362-366.
Myasthenia gravis (MG) is regarded as autoimmune disorder of neuromuscular transmission and apparently is due to formation of humoral antibody that cross-link to acetylcholine receptor at skeletal muscle end plate....
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A t(8;9)(p22;p24)/PCM1-JAK2 Translocation in a Patient With Myeloproliferative Neoplasm and Myeloid Sarcoma: First Report in Korea

Song I, Lee DH, Lee JH, Jang S, Huh JR, Seo EJ

No abstract available.
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A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis

Park KH, Kwon SS, Chung MH, Kim J, Lee HJ, Min JW, Kim YH

  • KMID: 2319901
  • Tuberc Respir Dis.
  • 2012 Aug;73(2):115-121.
Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic...
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The Effects of Iodide on the Cellular Functions and Expression of Thyroid Autoantigens in Thyroid Cells

Park YJ, Park ES, Kim TY, Jung HS, Park HK, Park DJ, Kim WB, Shin CS, Park KS, Kim SY, Lee HK, Cho BY

  • KMID: 1999184
  • J Korean Soc Endocrinol.
  • 2002 Feb;17(1):69-78.
BACKGROUND: Iodide has been known to control the function and the growth of the thyroid gland, and to be used as a substrate of thyroid hormone. Moreover, it has been...
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Autoantigenic Role of Variant Thyroperoxidase

Shong YK, Moon DH, Kim GS

  • KMID: 2461605
  • J Korean Soc Endocrinol.
  • 1996 Mar;11(1):61-67.
Background: Thyroperoxidase(TPO) is one of the most important autoantigens in autoimmune thyroid disorders and autoantibody to TPO is found in almost every patients with various autoimmune thyroid diseases. Human TPO...
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Engulfment signals and the phagocytic machinery for apoptotic cell clearance

Park SY, Kim IS

The clearance of apoptotic cells is an essential process for tissue homeostasis. To this end, cells undergoing apoptosis must display engulfment signals, such as ‘find-me' and ‘eat-me' signals. Engulfment signals...
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Disease-specific Proteins from Rheumatoid Arthritis Patients

Kim CW, Cho EH, Lee YJ, Kim YH, Hah YS, Kim DR

Rheumatoid arthritis (RA) is a chronic inflammatiory disease that mainly destroys cartilages or bones at the joints. This inflammatory disorder is initiated by self-attack using own immune system, but the...
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B Cell Targeted Therapy in Rheumatic Disease

Suh CH

B cells play an important role in the pathogenesis of autoimmune disease. B cells not only produce pathogenic autoantibodies, but also present self-antigens to T cells and provide costimulatory signals...
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Anti-Enteric Neuronal Antibodies and the Irritable Bowel Syndrome

Wood JD, Liu S, Drossman D, Ringel Y, Whitehead

  • KMID: 2325863
  • J Neurogastroenterol Motil.
  • 2012 Jan;18(1):78-85.
BACKGROUND/AIMS: Functional gastrointestinal disorders are those in which no abnormal metabolic or physical processes, which can account for the symptoms, can be identified. The irritable bowel syndrome (IBS) is a...
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The Effects of Interferon -gamma on the Expression of Bullous Pemphigoid Antigen Genes in Cultured Keratinocytes

Ryoo YW, Shin MS, Lee KS

  • KMID: 2250853
  • Korean J Dermatol.
  • 2002 Mar;40(3):235-243.
BACKGROUND: Interferon-gamma(IFN-gamma) has been shown to regulate epidermal keratinocyte growth and differentiation and can be isolated from subepidermal vesicles in bullous pemphigoid (BP) patients. In general, the IFN-gamma effects ate...
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Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens

Kashiwakura Ji, Okayama Y, Furue M, Kabashima , Shimada S, Ra C, Siraganian RP, Kawakami Y, Kawakami T

PURPOSE: Monomeric IgE molecules, when bound to the high-affinity receptor, exhibit a vast heterogeneity in their ability to induce survival promotion and cytokine production in mast cells. At one end...
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The Changes of Expression of Thyroid Specific Antigens in Aging

Park YJ, Park ES, Kim TY, Kim SW, Park HK, Park DJ, Kim WB, Shin CS, Park KS, Kim SY, Park SC, Lee HK, Cho BY

  • KMID: 1837609
  • J Korean Soc Endocrinol.
  • 2001 Oct;16(4-5):457-466.
BACKGROUND: With the prevalence of serum antithyroglobulin(anti-TG) and antithyroperoxidase(anti-TPO) autoantibodies increasing with age, it has been suggested that changes of thyroid autoimmunity with aging are associated with endemic iodine intake....
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Antigenicity of the Male Accessory Sexual Glands I. An Effect of the Homologous Prostatic Extract on the Male Sexual Glands in Rat

Hong SH, Kim SC

  • KMID: 2289589
  • Korean J Urol.
  • 1984 Aug;25(4):523-528.
The immunologic properties of the male accessory sexual glands have been the subject of intensive research in the recent years. Hence, the ability of the male accessory sexual gland autoantigens...
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Follicular Helper T (Tfh) Cells in Autoimmune Diseases and Allograft Rejection

Jeon YH, Choi YS

Production of high affinity antibodies for antigens is a critical component for the immune system to fight off infectious pathogens. However, it could be detrimental to our body when the...
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