J Korean Child Neurol Soc.
2004 Nov;12(2):203-206.
Aseptic Meningitis Associated with Intravenous Immunoglobulin Therapy for Myasthenia Gravis : A Report of Two Cases
- Affiliations
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- 1Department of Pediatrics, Mirae Children's Hospital, Korea. drkimjs@hanmail.net
- 2Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea.
Abstract
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Intravenous immunoglobulin (IVIG) is widely used to treat various neurologic or autoimmune disorders in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. We describe two girls, aged 2 and 8 years, with myasthenia gravis who suffered from aseptic meningitis after an administration of high-dose IVIG. Any other etiologic agent were identified in neither case. Both patients recovered completely within a few days and left no sequelae. To our knowledge, these are the first such reported cases in children with myasthenia gravis.