J Korean Child Neurol Soc.  2004 Nov;12(2):203-206.

Aseptic Meningitis Associated with Intravenous Immunoglobulin Therapy for Myasthenia Gravis : A Report of Two Cases

Affiliations
  • 1Department of Pediatrics, Mirae Children's Hospital, Korea. drkimjs@hanmail.net
  • 2Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea.

Abstract

Intravenous immunoglobulin (IVIG) is widely used to treat various neurologic or autoimmune disorders in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. We describe two girls, aged 2 and 8 years, with myasthenia gravis who suffered from aseptic meningitis after an administration of high-dose IVIG. Any other etiologic agent were identified in neither case. Both patients recovered completely within a few days and left no sequelae. To our knowledge, these are the first such reported cases in children with myasthenia gravis.

Keyword

Immunoglobulin; Meningitis; Myasthenia gravis; Child

MeSH Terms

Child
Female
Humans
Immunization, Passive*
Immunoglobulins*
Immunoglobulins, Intravenous
Meningitis
Meningitis, Aseptic*
Myasthenia Gravis*
Immunoglobulins
Immunoglobulins, Intravenous
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