J Korean Neurol Assoc.  2009 Aug;27(3):264-267.

Central Pontine Myelinolysis Presenting With Cerebellar Ataxia

Affiliations
  • 1Department of Neurology, Collage of Medicine, Chonbuk National University, Jeonju, Korea. ohsun@chonbuk.ac.kr

Abstract

Central pontine myelinolysis (CPM) is a neurologic disorder that is usually related to rapid correction of hyponatremia and chronic alcoholism. CPM involves concentrated, symmetric, noninflammatory demyelination within the central pons; this pathology also occurs in extrapontine regions. Frequently observed clinical manifestations are sudden weakness, dysphagia, dysarthria, loss of consciousness, and locked-in syndrome. We describe herein a case of CPM predominated by cerebellar signs without typical symptoms, but with involvement of the cerebellum or cerebellar peduncle.

Keyword

Central pontine myelinolysis (CPM); Cerebellar ataxia

MeSH Terms

Alcoholism
Cerebellar Ataxia
Cerebellum
Deglutition Disorders
Demyelinating Diseases
Dysarthria
Hyponatremia
Myelinolysis, Central Pontine
Nervous System Diseases
Quadriplegia
Unconsciousness
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