Genomics Inform.  2013 Mar;11(1):7-14. 10.5808/GI.2013.11.1.7.

Perspectives of International Human Epigenome Consortium

• Bae JB

• KMID: 1806265
• DOI: http://doi.org/10.5808/GI.2013.11.1.7

Abstract

As the International Human Epigenome Consortium (IHEC) launched officially at the 2010 Washington meeting, a giant step toward the conquest of unexplored regions of the human genome has begun. IHEC aims at the production of 1,000 reference epigenomes to the international scientific community for next 7-10 years. Seven member institutions, including South Korea, Korea National Institute of Health (KNIH), will produce 25-200 reference epigenomes individually, and the produced data will be publically available by using a data center. Epigenome data will cover from whole genome bisulfite sequencing, histone modification, and chromatin access information to miRNA-seq. The final goal of IHEC is the production of reference maps of human epigenomes for key cellular status relevant to health and disease.

Keyword

chromatin; DNA methylayion; histones; methylome; microRNAs

MeSH Terms

Chromatin
Genome
Genome, Human
Histones
Humans
Korea
MicroRNAs
Republic of Korea
Sulfites
Washington
Chromatin
Histones
MicroRNAs
Sulfites