Clin Exp Reprod Med.  2014 Sep;41(3):137-139. 10.5653/cerm.2014.41.3.137.

An effective method for improving outcomes in patients with a fertilization defect

Affiliations
  • 1Maria Reproductive Center, Department of Obstetrics and Gynecology, Maria Fertility Hospital, Seoul, Korea. dahamaria@naver.com
  • 2Maria Research Center, Seoul, Korea.

Abstract

The effect of artificial oocyte activation (AOA) with a calcium ionophore on intracytoplasmic morphologically selected sperm injection (IMSI) was examined in patients with histories of repeated failed implantation attempts. Four singleton pregnancies and one twin pregnancy were obtained after embryos transfer (5/14, 35.7%). Therefore, AOA combined with IMSI can be considered an option for cycles with a fertilization defect and recurrent implantation failures.

Keyword

Artificial oocyte activation; Intracytoplasmic morphologically selected sperm injection; Recurrent implantation failures

MeSH Terms

Calcium
Embryonic Structures
Fertilization*
Humans
Oocytes
Pregnancy
Pregnancy, Twin
Spermatozoa
Calcium
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