Clin Endosc.  2013 Mar;46(2):172-177. 10.5946/ce.2013.46.2.172.

Endoscopic Ultrasound Elastography for the Pancreas in Korea: A Preliminary Single Center Study

  • 1Institute for Digestive Research, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
  • 2Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.


Endoscopic ultrasound elastography (EUS-EG) has been widely used for the evaluation of pancreatic cancer in the Western world. To date, there is very little experience with EUS-EG in Korea. We described the results of comparison between normal pancreas and pancreatic cancer in Korea.
The present study was performed at a tertiary hospital on 35 subjects comprising 20 with normal pancreas (control group) and 15 with pancreatic cancer (disease group). We compared the EUS-EG performance of the two groups.
The pancreas in the control group showed a mean elasticity value of 0.53% (95% confidence interval [CI], 0.45 to 0.61). The elasticity value was higher than that previously reported from Western country (0.47%; 95% CI, 0.38 to 0.57). In the disease group, the mean elasticity value of pancreatic lesions was 0.02% (95% CI, 0.01 to 0.02). The mean elasticity value of the disease group was significantly lower than that of the control group (p<0.0001).
EUS-EG could be a highly sensitive diagnostic modality for pancreatic cancer in Korea with little EUS-EG experience. We also provided the reference range of elasticity value of normal pancreas, which might be valuable in the interpretation of pancreatic elasticity data for Korean adults.


Elasticity imaging techniques; Endosonography; Pancreas

MeSH Terms

Elasticity Imaging Techniques
Pancreatic Neoplasms
Reference Values
Tertiary Care Centers
Western World


  • Fig. 1 Elasticity measurements of the pancreas in the control group. (A) Normal-appearing pancreas on B-mode. (B) Green color with homogeneous distribution throughout the pancreatic parenchyma. (C) Two areas (A and B) were selected, among the regions of interest, for quantitative analysis.

  • Fig. 2 Elasticity measurements of pancreatic lesions in the disease group. (A) Dual views show the elastography mode (left panel) and B-mode (right panel). The area with green/heterogeneous pattern is representative of peripancreatic tissue, while the lesion with blue/heterogeneous pattern is representative of pancreatic cancer. (B) Area A was selected for quantitative analysis among the regions of interest.

  • Fig. 3 Comparison of mean elasticity values of the pancreas and pancreatic lesions between the control group and the disease group. The mean elasticity value of the disease group was significantly lower than that of the control group (p<0.001).

Cited by  3 articles

Elastography of the Pancreas, Current View
Christoph F. Dietrich, Michael Hocke
Clin Endosc. 2019;52(6):533-540.    doi: 10.5946/ce.2018.156.

Diagnostic Efficacy of Endoscopic Ultrasound Elastography in Differentiating Solid Pancreatic Lesions: A Single-Center Experience
Ahmed Youssef Altonbary, Hazem Hakim, Ahmed Mohamed El-Shamy
Clin Endosc. 2019;52(4):360-364.    doi: 10.5946/ce.2018.160.

Endoscopic Ultrasound Elastography for Pancreatic Cancer Diagnosis: A Step Forward?
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Clin Endosc. 2013;46(2):116-117.    doi: 10.5946/ce.2013.46.2.116.


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