Soonchunhyang Med Sci.  2015 Jun;21(1):28-30. 10.0000/sms.2015.21.1.28.

Acute Kidney Injury Arising from Severe Hyperemesis Gravidarum: Case Report with a Review of Literatures

Affiliations
  • 1Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. drsook@schmc.ac.kr

Abstract

Severe hyperemesis gravidarum is a rare but potentially life-threatening it left untreated. Its serious complications are dehydration, ketosis, alkalosis from loss of hydrochloric acid, hypokalemia, and compromised pre-renal acute kidney injury. We experienced a very rare case of a 20-year-old woman who presented to the emergency department with severe hyperemesis gravidarum associated with a loss of kidney function at 25 weeks' gestation. Her initial serum creatinine and blood urea nitrogen were 5.0 and 45.9 mg/dL, respectively. The patient underwent hemodialysis for three days and achieved a subsequent recovery of renal function. In conclusion, our case indicates that clinicians should be aware of the possibility of acute kidney injury associated with severe hyperemesis gravidarum although rare.

Keyword

Hyperemesis gravidarum; Acute kidney injury; Renal dialysis

MeSH Terms

Acute Kidney Injury*
Alkalosis
Blood Urea Nitrogen
Creatinine
Dehydration
Emergency Service, Hospital
Female
Humans
Hydrochloric Acid
Hyperemesis Gravidarum*
Hypokalemia
Ketosis
Kidney
Pregnancy
Renal Dialysis
Young Adult
Creatinine
Hydrochloric Acid
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