Korean J Obstet Gynecol.  2001 Oct;44(10):1909-1912.

A Case of Wernicke's Encephalopathy associated with Hyperemesis Gravidarum

• Choi YS
• Kim JO
• Lee SL
• Song SK
• Jo BC

Abstract

Hyperemesis gravidarum is characterized by severe nausea, vomiting followed by weight loss, dehydration, electrolyte imbalance and acid-base derangements. Its treatment was composed of adequate fluid therapy, electrolyte replacement and nutrient supply. In severe case, it also leads to a variety of neurological symptoms including confusion, gait disturbance and nystagmus, possibly due to thiamine deficiency and may result in so called Wernicke's disease. We have experienced a case of Wernicke's encephalopathy associated with severe hyperemesis gravidarum and this case is presented with a brief review of literature.

Keyword

Hyperemesis gravidarum; Wernicke's encephalopathy

MeSH Terms

Dehydration
Female
Fluid Therapy
Gait
Hyperemesis Gravidarum*
Nausea
Pregnancy
Thiamine Deficiency
Vomiting
Weight Loss
Wernicke Encephalopathy*