Soonchunhyang Med Sci.  2015 Jun;21(1):20-23. 10.0000/sms.2015.21.1.20.

Epstein-Barr Virus Positive Follicular Lymphoma of Lymph Node

• Choi IH
• Jin SY
• Kim DW
• Jeen YM
• Kim KH
• Won JH

• KMID: 1797806
• DOI: http://doi.org/10.0000/sms.2015.21.1.20

Abstract

Epstein-Barr virus (EBV) infection has been associated with a number of lymphoid malignancies, including endemic Burkitt's lymphoma, some classical Hodgkin's lymphoma, diffuse large B-cell lymphoma, extranodal NK/T cell lymphoma, and angioimmunoblastic T-cell lymphoma. A 59-year-old woman underwent an excisional biopsy for a left axillary mass under suspicion of malignant lymphoma. A preoperative radiological study revealed multiple enlarged lymph nodes at the left axilla, mesentery, and the left external iliac chain with hypermetabolism on a positron emission tomography-computed tomography scan. She was histologically diagnosed with EBV-positive follicular lymphoma (FL, grade 3a) and received the R-CHOP (rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, prednisone) chemotherapy regimen. Herein, we report a rare case of EBV associated FL of lymph node with its review of literature.

Keyword

Follicular lymphoma; Herpesvirus 4, human; Epstein-Barr virus-associated lymphoma

MeSH Terms

Axilla
Biopsy
Burkitt Lymphoma
Cyclophosphamide
Drug Therapy
Electrons
Female
Herpesvirus 4, Human*
Hodgkin Disease
Humans
Lymph Nodes*
Lymphoma
Lymphoma, B-Cell
Lymphoma, Follicular*
Lymphoma, T-Cell
Mesentery
Middle Aged
Vincristine
Cyclophosphamide
Vincristine