Korean J Med.
2004 Nov;67(Suppl 3):S836-S840.
A case of peripheral T-cell lymphoma with Reed-Sternberg like cells associated with Epstein-Barr virus
- Affiliations
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- 1Department of Internal Medicine, National Police Hospital, Seoul, Korea. drsykim@chol.com
- 2Department of Pathology, National Police Hospital, Seoul, Korea.
Abstract
- The Reed-Sternberg like cells (RS-like cells) are by no means specific to Hodgkin lymphoma, but they have been reported in various other lymphoproliferative disorders, including infectious mononucleosis. Many studies have postulated that Epstein-Barr virus (EBV) infection may play a role in the development of RS-like cells in non-Hodgkin's lymphoma. There are many accounts in the literature about these RS-like cells in lymph node aspirates and biopsies creating diagnostic confusion with Hodgkin lymphoma, but no report in Korea. We experienced a case of a 44 year-old male patient who had multiple lymph nodes enlargement with the history of treatment of Hodgkin lymphoma 15 years ago. At this time, this patient was diagnosed as peripheral T-cell lymphoma with RS-like cells associated with EBV in lymph node biopsy. Here, we report this case with a review of the relevant literature.
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