Korean J Gastroenterol.  2012 Jun;59(6):441-444. 10.4166/kjg.2012.59.6.441.

A Case of Sweet's Syndrome in a Patient with Liver Cirrhosis Caused by Chronic Hepatitis B

• Park CW
• Kim YJ
• Seo HJ
• Lee KI
• Jang BK
• Hwang JS
• Chung WJ

• KMID: 1792851
• DOI: http://doi.org/10.4166/kjg.2012.59.6.441

Abstract

Sweet's syndrome (SS), also known as acute febrile neutrophilic dermatosis, is characterized by the sudden onset of painful erythematous skin lesions together with fever and neutrophilia. SS can be associated with several disorders, such as malignancy, autoimmune disease, and infections. However, SS associated with liver cirrhosis is uncommon. We report a case of SS in a patient who was diagnosed with liver cirrhosis caused by chronic hepatitis B.

Keyword

Sweet's syndrome; Liver cirrhosis; Chronic hepatitis B

MeSH Terms

Hepatitis B, Chronic/complications/*diagnosis
Humans
Liver Cirrhosis/*diagnosis/etiology
Male
Middle Aged
Neutrophils/immunology/pathology
Skin Diseases/*diagnosis/pathology
Sweet Syndrome/*diagnosis/pathology
Tomography Scanners, X-Ray Computed

Figure

• 

  Fig. 1 Multiple tender, raised, annular erythematous lesions on the arms (A) and trunk (B). Round pustular lesions with central necrosis and skin ulcers on the left thigh (C).

• 

  Fig. 2 Abdominal computed tomography scan showed a shrunken liver, splenomegaly, and a moderate amount of ascites.

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  Fig. 3 Biopsy of a skin lesion showed dense neutrophilic infiltration into the dermis, without evidence of vasculitis (H&E, ×400).

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