Korean J Gastroenterol.
1999 Jan;33(1):148-152.
A Case of Overlap Syndromebetween Autoimmune Hepatitis and Primary Biliary Cirrhosis
Abstract
- Autoimmune hepatitis is an unresolving inflammation of the liver due to unknown cause. It is characterized by hypergammaglobulinemia, and autoantibodies in serum and the presence of hepatitis that is periportal or widespread on histologic examination. Patients with variant forms of autoimmune hepatitis have autoimmmune features, but do not satisfy the criteria for a definite or probable diagnosis of autoimmune hepatitis. In addition, they cannot be placed in another diagnostic category Such patients have features associated with both autoimmune hepatitis and another type of chronic liver disease (overlap syndromes) or findings that are incompatible with the diagnosis of autoimmune hepatitis according to the criteria codified by the international panels (outlier syndromes). In this report, we present one case of overlap syndrome between autoimmmune hepatitis and primary biliary cirrhosis.
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