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Decreased C-reactive protein induces abnormal vascular structure in a rat model of liver dysfunction induced by bile duct ligation

Jun JH, Choi JH, Bae SH, Oh SH, Kim GJ

BACKGROUND/AIMS: Chronic liver disease leads to liver fibrosis, and although the liver does have a certain regenerative capacity, this disease is associated with dysfunction of the liver vessels. C-reactive protein...
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Retrospective analysis of autoimmune hepatitis-primary biliary cirrhosis overlap syndrome in Korea: characteristics, treatments, and outcomes

Park Y, Cho Y, Cho EJ, Kim YJ

BACKGROUND/AIMS: Overlap syndrome of autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) (AIH-PBC overlap syndrome) is a rare disease that has not been clearly characterized in Korean patients. This study...
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Successful Treatment of Primary Biliary Cirrhosis with Adalimumab in a Patient with Overlap Syndrome

Han JY, Lee KH, Seo MR, Choi HJ

Primary biliary cirrhosis (PBC) is occasionally developed in patients with rheumatic diseases, such as systemic sclerosis or Sjogren's syndrome. However, there are a few reports of overlap syndrome with PBC....
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Prognostic indicators in primary biliary cirrhosis: significance of revised IAHG (International Autoimmune Hepatitis Group) score

Jung HE, Jang JY, Jeong SW, Kim JN, Jang HY, Cho YJ, Woo SA, Lee SH, Kim SG, Cha SW, Kim YS, Cho YD, Kim HS, Kim BS

BACKGROUND/AIMS: Primary biliary cirrhosis (PBC) is a slowly progressing autoimmune disease of the liver that is characterized by portal inflammation and immune-mediated destruction of the intrahepatic bile ducts. Serum total...
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Visceral Leishmaniasis Mimicking Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Systemic Lupus Erythematosus Overlap

Tunccan OG, Tufan A, Telli G, Akyurek N, Pamukcuoglu M, Yilmaz G, Hizel K

Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date,...
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The diagnosis and treatment of primary biliary cirrhosis

Kim KA, Jeong SH

Primary biliary cirrhosis (PBC) is a slowly progressive cholestatic liver disease of autoimmune etiology. The initial presentation of PBC is various from asymptomatic, abnormal liver biochemical tests to overt cirrhosis....
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The Primary Biliary Cirrhosis Presenting with Raynaud's Disease and Digital Necrosis

Hwang JY, Yoon H, Kang JS, Lee SA, Lee WJ, Lee KU, Park JY

Necrosis of the upper extremity occurs rarely in type 2 diabetic patients compared to lower extremity necrosis. We report a 69-year-old woman with type 2 diabetes mellitus who presented with...
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Prognosis of Korean patients with primary biliary cirrhosis

Song BC

No abstract available.
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A Case of Primary Biliary Cirrhosis in Association with an Overlap Syndrome of Systemic Sclerosis and Systemic Lupus Erythematosus

Yoon BY, Song HY, Lee JH, Kim KA

  • KMID: 2334888
  • J Korean Rheum Assoc.
  • 2009 Dec;16(4):338-343.
Primary biliary cirrhosis (PBC) is a slowly progressive autoimmune disease of the liver that is related to anti-mitochondria antibody and the disease is characterized by portal inflammation and immune-mediated destruction...
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Four cases of autoimmune cholangitis

Chung SK, Jang JY, Jeong SW, Shim CS, Kim BS, Jeen YM, Jin SY

  • KMID: 2305785
  • Korean J Med.
  • 2009 Dec;77(6):750-754.
Autoimmune cholangitis is a disease with clinicopathologic features of primary biliary cirrhosis without antimitochondrial antibodies and, frequently, with high antinuclear antibody titers. Alternative terms have been suggested, including antimitochondrial antibody-negative...
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A Case of Portopulmonary Hypertension Associated with Primary Biliary Cirrhosis

Kim SJ, Lee EJ, Jung KH, Kang EH, Lee SY, Lim HE, Yim HJ, Lee SY, Kim JH, Shin C, Shim JJ, In KH, Kang KH, Yoo SH

  • KMID: 2318946
  • Tuberc Respir Dis.
  • 2007 May;62(5):421-426.
Portopulmonary hypertension (PPHTN) is a clinically and pathophysiologically distinct complication of advanced liver disease. PPHTN is characterized by the development of pulmonary arterial hypertension in association with advanced hepatic disease-related...
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A Case of Polymyositis Associated with Primary Biliary Cirrhosis

Park TJ, Choi GS, Park HJ, Joe DY, Chung JW, Park HS, Cheong JY, Kim YB, Shim C, Suh CH

  • KMID: 2202213
  • J Korean Rheum Assoc.
  • 2006 Dec;13(4):348-352.
The coexistence of polymyositis and primary biliary cirrhosis is rare. Both are characterized by chronic inflammation and immunological abnormalities. We report a case of 54-year-old female patient presenting with these...
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Primary Biliary Cirrhosis

Chon CY, Park JY

  • KMID: 760668
  • Korean J Hepatol.
  • 2006 Sep;12(3):364-372.
Primary biliary cirrhosis (PBC) is a chronic cholestatic autoimmune liver disease that predominantly affects middle-aged women. It is characterized by slowly progressive destruction of the small intrahepatic bile ducts together...
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A case of primary biliary cirrhosis associated with autoimmune primary hypothyroidism

Kwon SK, Yang SY

  • KMID: 1984649
  • Korean J Med.
  • 2005 Jul;69(1):96-100.
Primary biliary cirrhosis (PBC) is an idiopathic chronic non-suppurative destructive inflammation of intrahepatic bile ducts and rare in Korea. Although its pathogenesis is not fully understood, immunologic dysregulation is suspected...
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Determination of Anti-mitochondrial Antibody with M2 Antigens

Kim KH, Han JY, Kim JM, Jang JS, Lee SW, Lee JH, Han SY

  • KMID: 2038245
  • Korean J Lab Med.
  • 2005 Apr;25(2):104-110.
BACKGROUND: Anti-mitochondrial antibodies (AMA) are a hallmark of primary biliary cirrhosis (PBC); however, low titers of AMA are also detected in some patients without PBC. We evaluated the clinical value...
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Differential Expression of Promyelocytic Leukemia Protein in Autoimmune Liver Diseases

Kim HJ, Kim JS, Lee YS, Chung YH, Lee HJ, Suh DJ, Kim CJ, Yu E

  • KMID: 2277689
  • Korean J Pathol.
  • 2004 Dec;38(6):357-363.
BACKGROUND: Promyelocytic leukemia protein (PML) is a primary biliary cirrhosis (PBC)-specific autoantigen. Anti-PML antibody is analyzed using cultured cells with patient sera, however, PML expression has rarely been examined in...
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A Case of Nodular Regenerative Hyperplasia of Liver that mimicked Primary Biliary Cirrhosis

Shim SG, Sohn JH, Lee JW, Chung YW, Paik CH, Kim JP, Jeon YC, Han DS, Hahm JS, Lee DH, Kee CS, Oh YH

  • KMID: 760568
  • Korean J Hepatol.
  • 2004 Dec;10(4):313-318.
Nodular regenerative hyperplasia (NRH) of the liver is a rare disease that is characterized by multiple regenerative nodules in the hepatic parenchyma without fibrosis. The exact pathogenesis of NRH has...
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A case of the overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis

Ahn SJ, Kwon BP, Lee SH, Lee TY, Jang JS, Jeong JS, Han SY

  • KMID: 1984903
  • Korean J Med.
  • 2004 Feb;66(2):214-218.
Primary biliary cirrhosis and autoimmune hepatitis are the two main immune-mediated liver diseases. They are generally differentiated easily on the basis of clinical, biochemical, serological, and histological findings. Occasionally, the...
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A case of primary biliary cirrhosis manifestated with idiopathic thrombocytopenic purpura and Sjogren's syndrome

Woo TW, Kim BH, Shim J, Kim YH, Cho KS

  • KMID: 2252693
  • Korean J Med.
  • 2004 Jan;66(1):80-85.
Primary biliary cirrhosis (PBC) is rare in Korea. Although its pathogenesis is not fully understood, immunologic dysregulation is suspected because it is frequently associated with other immunologic disorders. A few...
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A Case of Primary Biliary Cirrhosis in Association with Sjorgen's Syndrome Developing Features of Systemic Lupus Erythematosus

Lee CG, Chang HK, Kim SY, Kang HH, Kim DJ, Chang CK, Maeng JH, Lee HS, Park PG, Chung JG

  • KMID: 1587039
  • J Korean Rheum Assoc.
  • 2001 Mar;8(1):59-63.
Primary biliary cirrhosis (PBC)is a chronic inflammatory disease characterized by fibrous obliteration of intrahepatic bile ductules.Although the etiopathogenesis of PBC remains unclear,several studies suggest that a disordered immune response may...
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