Korean J Pain.  2013 Jan;26(1):80-83. 10.3344/kjp.2013.26.1.80.

Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus: A Case Report

• Bae HM
• Park YJ
• Kim YH
• Moon DE

• KMID: 1779030
• DOI: http://doi.org/10.3344/kjp.2013.26.1.80

Abstract

Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommend gradual titration when initiating treatment with carbamazepine.

Keyword

carbamazepine; drug hypersensitivity reaction; Stevens-Johnson syndrome; trigerminal neuralgia

MeSH Terms

Carbamazepine
Humans
Pruritus
Skin
Stevens-Johnson Syndrome
Trigeminal Neuralgia
Carbamazepine

Figure

• 

  Fig. 1 Skin and mucosa of our patient: ruptured bullae over the right arm and oral mucosa were involved by SJS.

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