Korean J Intern Med.  2013 May;28(3):263-273. 10.3904/kjim.2013.28.3.263.

Diagnosis and therapy of multiple myeloma

• Palumbo A
• Cerrato C

• KMID: 1776445
• DOI: http://doi.org/10.3904/kjim.2013.28.3.263

Abstract

Many advances in the treatment of multiple myeloma have been made due to the use of transplantation and the introduction of novel agents including thalidomide, lenalidomide, and bortezomib. The first step is recognizing the symptoms and starting prompt treatment. Different strategies should be selected for young and elderly subjects. Young patients are commonly eligible for transplantation, which is now considered the standard approach for this setting, and various inductions therapies containing novel agents are available before transplantation. Elderly patients are usually not eligible for transplantation, and gentler approaches with new drugs combinations are used for their treatment.

Keyword

Multiple myeloma; Thalidomide; Lenalidomide; Bortezomib; Induction therapy

MeSH Terms

Age Factors
Antineoplastic Agents/therapeutic use
Boronic Acids/therapeutic use
Humans
Immunologic Factors/therapeutic use
Multiple Myeloma/diagnosis/epidemiology/*therapy
Prognosis
Pyrazines/therapeutic use
Stem Cell Transplantation
Thalidomide/analogs & derivatives/therapeutic use
Antineoplastic Agents
Boronic Acids
Immunologic Factors
Pyrazines
Thalidomide