J Korean Neurol Assoc.
2015 Feb;33(1):33-35.
Recurrent Transient Global Amnesia in a Hot and Humid Machinery Room
- Affiliations
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- 1Departments of Neurology, Chungbuk National University College of Medicine, Cheongju, Korea. jissn@hanmail.net
Abstract
- Transient global amnesia (TGA) is characterized by abrupt onset temporary dysfunction of anterograde and retrograde amnesia without other neurologic deficits. We encountered a 53-year-old man who developed recurrent TGA while working in a hot and humid machinery room (33degrees C and 64% relative humidity). Heat exposure and physical exertion may facilitate the leakage of cytokines into the systemic circulation so as to cause a cerebral endothelial insult. Functional insufficiency of the hippocampus and its connections caused by physical and environmental factors may be related to recurrent attacks.