Ann Clin Neurophysiol.  2023 Oct;25(2):103-105. 10.14253/acn.2023.25.2.103.

Recurrent transient amnesia: a case of transient epileptic amnesia misdiag-nosed as transient global amnesia

Affiliations
  • 1Department of Neurology, Inje University Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea

Abstract

Transient epileptic amnesia and transient global amnesia both exhibit temporary memory loss. The lack of clues of epileptic events and the absence of epileptiform abnormalities in electroencephalography, a clear brain lesion, and interictal cognitive decline can make diagnoses challenging. Here we present a middle-aged female who experienced long-term recurrent transient epileptic amnesia with subtle epileptic features over a period of 3 years.


Figure

  • Fig. 1. (A) Brain oblique coronal T2-weighted fluid-attenuated inversion-recovery magnetic resonance imaging produced unremarkable findings in the mesial temporal lobes, including the hippocampus. (B) Interictal brain perfusion single-positron-emission computed tomography showed decreased perfusion in the left anterior temporal lobe (white arrow), suggesting an epileptic focus. (C) Electroencephalography showed epileptiform discharges in the left anterior temporal area (black arrows).


Reference

1. Butler CR, Graham KS, Hodges JR, Kapur N, Wardlaw JM, Zeman AZ. The syndrome of transient epileptic amnesia. Ann Neurol. 2007; 61:587–598.
Article
2. Mosbah A, Tramoni E, Guedj E, Aubert S, Daquin G, Ceccaldi M, et al. Clinical, neuropsychological, and metabolic characteristics of transient epileptic amnesia syndrome. Epilepsia. 2014; 55:699–706.
Article
3. Ramanan VK, Morris KA, Graff-Radford J, Jones DT, Burkholder DB, Britton JW, et al. Transient epileptic amnesia: a treatable cause of spells associated with persistent cognitive symptoms. Front Neurol. 2019; 10:939.
Article
4. Gallassi R. Epileptic amnesic syndrome: an update and further considerations. Epilepsia. 2006; 47 Suppl 2:103–105.
Article
5. Cho S, Lee WW, Kang K, Park JM, Kim BK, Kwon O, et al. Transient epileptic amnesia with preserved consciousness: a report of two cases. J Epilepsy Res. 2017; 7:54–56.
Article
6. Bartsch T, Butler C. Transient amnesic syndromes. Nat Rev Neurol. 2013; 9:86–97.
Article
7. Tynas R, Panegyres PK. Factors determining recurrence in transient global amnesia. BMC Neurol. 2020; 20:83.
Article
8. Kang HG, Chung JY, Ha JM, Choo IS, Kim HW, Kim JH, et al. Comparison of clinical characteristics between transient global amnesia with and without acute focal lesion in hippocampus. J Korean Neurol Assoc. 2016; 34:312–317.
Article
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