Korean J Anesthesiol.  2011 Feb;60(2):124-127. 10.4097/kjae.2011.60.2.124.

Anesthetic experience of a patient with Ohtahara syndrome: A case report

• Choi EM
• Min KT
• Cho JS
• Choi SH

• KMID: 1766531
• DOI: http://doi.org/10.4097/kjae.2011.60.2.124

Abstract

Ohtahara syndrome (OS) is a rare epileptic encephalopathy that is characterized by an abnormal electroencephalogram (EEG) and intractable seizures in the neonatal and early infantile period. The patient of this reported case was delivered normally at 39 weeks of gestation without any complication. One week after birth, seizures that were refractory to anticonvulsants started with repetitive clustered tonic spasms. The child had no abnormal findings on the initial laboratory investigations. But he was diagnosed with OS according to the frequent tonic spasms, an abnormal EEG pattern of suppression-burst and magnetic resonance imaging of cortical dysplasia. He was planned to undergo an operation for brain lesion. This report describes our experience with the general anesthetic management when we performed craniotomy and right hemispherotomy for a patient with OS.

Keyword

Infantile epileptic syndrome; Ohtahara syndrome; Suppression-burst

MeSH Terms

Anticonvulsants
Brain
Child
Craniotomy
Electroencephalography
Humans
Magnetic Resonance Imaging
Malformations of Cortical Development
Parturition
Pregnancy
Seizures
Spasm
Anticonvulsants