J Korean Pediatr Soc.  1996 May;39(5):722-726.

Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child

• Lee R
• Ha IS
• Cheong HI
• Choi Y

Abstract

Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography. She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3 and high anti-ds-DNA Ab, but did not meet whole criteria. And lupus anticoagulant was positive. She was treated with anticoagulants(heparin and wafarin) and prednisolone. Antiphospholipid antibody(lupus anticoagulant and anticardiolipin antibody) should be checked in children with thrombosis occurring without a known predisposing cause.

Keyword

Antiphospholipid syndrome; Pulmonary embolism; Deep Vein thrombosis

MeSH Terms

Adolescent
Antibodies, Antinuclear
Antiphospholipid Syndrome*
Child*
Diagnosis
Dyspnea
Female
Femoral Vein
Humans
Lung
Lupus Coagulation Inhibitor
Prednisolone
Pulmonary Embolism*
Thrombocytopenia
Thrombosis
Ultrasonography
Venous Thrombosis*
Antibodies, Antinuclear
Lupus Coagulation Inhibitor
Prednisolone