Anesth Pain Med.  2008 Jan;3(1):55-58.

Tumor Induced Disseminated Intravascular Coagulation : A case report

• Kim HJ
• Kim DW
• Shin JC
• Shim JC
• Suh JK
• Yi HJ

Abstract

Neuroblastoma, relatively common pediatric nervous system malignancy, presents as in various clinical aspects, including mass, pain, fever, weight loss, and infrequently anemia and hepatopathy. Hematologic abnormalities are also brought about according to the disease stage or pancytopenia due to radiation, mainly in the form of coagulopathy. We herein briefly report a rare case of stage IV neuroblastoma accompanied by chronic or subacute disseminated intravascular coagulation in a 5-year-old boy. Despite apparently normal coagulation profiles, we could not conduct routine invasive vascular procedures after induction of general anesthesia because of unexplained bleeding diathesis. Anesthesiologists should be alert to this kind of unexpected but potentially lethal complication and prepare to avoid mishaps.

Keyword

bleeding diathesis; disseminated intravascular coagulation; neuroblastoma

MeSH Terms

Anemia
Anesthesia, General
Disease Susceptibility
Disseminated Intravascular Coagulation
Fever
Hemorrhage
Nervous System
Neuroblastoma
Pancytopenia
Preschool Child
Weight Loss