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Nusinersen as a Therapeutic Agent for Spinal Muscular Atrophy

Li Q

The reduction of survival motor neuron (SMN) protein causes spinal muscular atrophy (SMA), an autosomal recessive neuromuscular disease. Nusinersen is an antisense oligonucleotide, approved by the FDA, which specifically binds...
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Changes in attention variables in those who treated with anticholinergic agents for nonmonosymptomatic enuresis

Jang G, Im YJ, Suh J, Park K

PURPOSE: Brain dysfunction related to areas regarding attention and arousal may occur not only in patients with attention-deficit/hyperactivity disorder (ADHD) but also in patients with enuresis and daytime symptoms. This...
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Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats

Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK

Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma...
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Distribution of Trauma Deaths in a Province of Korea: Is “Trimodal” Distribution Relevant Today?

Hwang K, Jung K, Kwon J, Moon J, Heo Y, Lee JC, Huh Y

PURPOSE: This study was designed to provide a basis for building a master plan for a regional trauma system by analyzing the distribution of trauma deaths in the most populous...
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Real world effectiveness and safety of pegylated liposomal doxorubicin in platinum-sensitive recurrent ovarian, fallopian, or primary peritoneal cancer: a Korean multicenter retrospective cohort study

Park SJ, Kim J, Kim HS, Lee JW, Chang HK, Lee KH, Kim DY, Kim S, Chang SJ, Han SS, Park SY, Shim SH

OBJECTIVE: To evaluate the effectiveness and safety of the combination of pegylated liposomal doxorubicin with carboplatin (CD) compared with those of carboplatin and paclitaxel (CP) for platinum-sensitive recurrent ovarian, fallopian,...
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Feasibility of Robot-Assisted Gait Training with an End-Effector Type Device for Various Neurologic Disorders

Choi S, Kim SW, Jeon HR, Lee JS, Kim DY, Lee JW

Robots are being used to assist the recovery of walking ability for patients with neurologic disorders. This study aimed to evaluate the feasibility and functional improvement of training with robot-assisted...
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Opioids and Antidepressants for Pain Control in Musculoskeletal Disease

Park SJ, Kim WS, Jang T

The progression of aging and the increase in musculoskeletal diseases have led to an increase in invasive treatment methods, including various surgical methods, but conservative treatment should be attempted before...
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Disease-Specific Mortality and Prevalence Trends in Korea, 2002–2015

Shin Y, Park B, Lee HA, Park B, Han H, Choi EJ, Kim NE, Park H

BACKGROUND: Evaluation of mortality and prevalence trends is important for health planning and priority decision-making in health policy. This study was performed to examine disease-specific mortality and prevalence trends for...
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Non-celiac Gluten Sensitivity

Cha RR, Kim HJ

Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms...
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MR Neurography: Current Several Issues for Novice Radiologists

Ha DH

Magnetic resonance neurography (MRN) has been increasingly used in recent years for the assessment of peripheral neuropathies. Fat suppression T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) have typically been used...
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Heterotrophic Ossification after Aggressive Rehabilitation in Patients with Trauma: A Case Report

Sim JA, Yoon YC, Baek SH

Heterotrophic ossification (HO) is a reactive disease presenting the formation of mature lamellar bone in soft tissues. It is known to occur following surgery, soft tissue injury, or central nervous...
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Immune-Mediated Peripheral Neuropathy in Patients with Diffuse Panbronchiolitis

Kang YR, Nam TS, Lee KH, Kim S, Park HJ, Lee SJ, Lee SH, Kim BC

No abstract available.
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Different Quantitative Interferon-γ Response in Active Tuberculosis of Various Primary Infection Sites

Lee H, Kim KH

BACKGROUND: The quantitative interferon (IFN)-γ response in the IFN-γ release assay (IGRA) has been investigated to predict progression from Mycobacterium tuberculosis infection to active tuberculosis (TB). However, the significance of...
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Diabetic Peripheral Neuropathy as a Risk Factor for Sarcopenia

Oh TJ, Song Y, Moon JH, Choi SH, Jang HC

BACKGROUND: Diabetic peripheral neuropathy (DPN) is prevalent in patients with type 2 diabetes, and its prevalence increases with age. A previous study demonstrated the association between DPN and muscle dysfunction;...
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Full mouth rehabilitation for a Parkinson's diseases patient with chronic periodontitis: a case report

Koh ES, Kim JJ, Baik J, Cha HS, Lee JH

Parkinson's disease is a neurological disorder characterized by tremor, bradykinesia, akinesia, postural instability, and muscular rigidity, which is caused by the depletion of neurotransmitters such as dopamine. Cooperative dental treatment...
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Recurrent Ipsilateral Breast Sparganosis: A Case Report

Ahn JH, Yi JY, Kim SJ, Hur MH

Sparganosis is a rare parasitic infection that can infect the abdominal wall, extremities, urogenital system, and/or central nervous system. Because the incidence of sparganosis is less than 2% of all...
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A Case of Thyroarytenoid Myoneurectomy Using LASER and Monopolar Electrical Device in Spasmodic Dysphonia

Lee SJ, Jung SY, Chung SM, Kim HS

Spasmodic dysphonia is a focal laryngeal dystonia that results in involuntary spasms during speech. The etiology of spasmodic dysphonia is not yet defined, but it is presumed to be a...
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Transvenous Onyx embolization of cavernous sinus dural arteriovenous fistula using a balloon catheter in the arterial side for flow control

Kang CH, Roh J, Yeom JA, Lee SW, Baik SK

BACKGROUND: Cavernous sinus (CS) dural arteriovenous fistulas (DAVFs) are abnormal arteriovenous shunts involving the dura mater, located within or near the walls of the CS. Transvenous embolization is considered to...
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Meta-analysis on the Efficacy of Glutamate Receptor Antagonists for Acute Migraine Treatment

Kim S, Baek IH

BACKGROUND: Glutamate is implicated in the pathophysiology of migraine, a common neurological disorder. Therefore, glutamate receptor antagonists (GluRAs) have been suggested as a novel migraine treatment that are able to...
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White matter hyperintensities in migraine: a review

Lee MJ, Moon S, Chung CS

Migraine is a neurological disorder characterized by recurrent spells of headache accompanied by brain symptoms such as nausea, vomiting, photophobia, and phonophobia. White matter hyperintensity (WMH) is the most frequent...
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