Korean J Pathol.
1989 Dec;23(4):470-475.
Ki-1 Positive T-Cell Lymphoma of Bone in a Child
- Affiliations
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- 1Department of Pathology, National Medical Center, Seoul, Korea.
- 2Department of Pathology, School of Medicine, Hanyang University, Seoul, Korea.
Abstract
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Ki-1 monoclonal antibody is a well known marker for Reed-Sternberg cells in Hodgkin's disease, but also occasionally reacts with activated lymphoid cells of either benign or malignant nature. Recently, Ki-1 antibody positive Non-Hodgkin's lymphoma, usually of large cell and/or polymorphous type, has been reported in the lymph nodes, skin, soft tissue, and stomach, but not in the bone. We report a case of multifocal primary bone lymphoma in a seven-year old body involving the left shoulder and right frontal bone, which proved to be a large cell, polymorphous lymphoma, helper T-cell type expressing Ki-1 antigen.