Korean J Pathol.  1989 Dec;23(4):470-475.

Ki-1 Positive T-Cell Lymphoma of Bone in a Child

Affiliations
  • 1Department of Pathology, National Medical Center, Seoul, Korea.
  • 2Department of Pathology, School of Medicine, Hanyang University, Seoul, Korea.

Abstract

Ki-1 monoclonal antibody is a well known marker for Reed-Sternberg cells in Hodgkin's disease, but also occasionally reacts with activated lymphoid cells of either benign or malignant nature. Recently, Ki-1 antibody positive Non-Hodgkin's lymphoma, usually of large cell and/or polymorphous type, has been reported in the lymph nodes, skin, soft tissue, and stomach, but not in the bone. We report a case of multifocal primary bone lymphoma in a seven-year old body involving the left shoulder and right frontal bone, which proved to be a large cell, polymorphous lymphoma, helper T-cell type expressing Ki-1 antigen.

Keyword

Primary bone lymphoma; Ki-1 positive T-cell lymphoma

MeSH Terms

Antigens, CD30
Child*
Frontal Bone
Hodgkin Disease
Humans
Lymph Nodes
Lymphocytes
Lymphoma
Lymphoma, Non-Hodgkin
Lymphoma, T-Cell*
Reed-Sternberg Cells
Shoulder
Skin
Stomach
T-Lymphocytes*
T-Lymphocytes, Helper-Inducer
Antigens, CD30
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