Korean J Dermatol.  1993 Jun;31(3):444-448.

A case of Ki-1 positive large-cell lymphoma

Abstract

In 1985, Stein et al, indentified an anaplastic large-cell malignant lymphoma that was distinctive because of the diffuse dermal infiltration of pleomorphic large lymphocytes, sinus growth pattern, and reactivity with the monoclonal antibody Ki-1(CD30). The clinical feature; distinguishing anaplastic large-cell Ki-1 lymphoma include a young median age, frequent peripheral adenopathy with sparing of the mediastinum, and extranodal disease with skin the most common sitc of involvement. We report a case of Ki-1 postive large-cell lymphoma in a 74-year-old male patient who presented with multiple ulcerated nodules on the right shin area.

Keyword

Ki-1 positive large-cell lymphoma; monoclonal antibody Ki-l(CO30)

MeSH Terms

Aged
Humans
Lymphocytes
Lymphoma*
Lymphoma, Large-Cell, Anaplastic
Male
Mediastinum
Skin
Ulcer
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