J Korean Med Assoc.  2005 Feb;48(2):169-178. 10.5124/jkma.2005.48.2.169.

Pathogenesis and Management of Non-alcoholic Steatohepatitis

• Park SH
• Park CK

• KMID: 1723889
• DOI: http://doi.org/10.5124/jkma.2005.48.2.169

Abstract

No abstract available.

Keyword

NASH; Insulin resistance; Oxidative stress; Management

MeSH Terms

Fatty Liver*
Insulin Resistance
Oxidative Stress

Figure

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  Figure 1

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  Figure 2 Fatty acids impair the tyrosine phosphorylation of IRS-1. Tyrosine phosphorylation of insulin receptor substrates is a general mechanism of insulin action. Deactivating insulin receptor substrates such as IRS-1, leading to insulin resistance.

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