Korean J Dermatol.  1992 Apr;30(2):211-216.

Primary cutaneous aspergillosis in a leukemia child

Abstract

Following chemotherapy for acute myelomoncytic leukemia, an 3-year-old boy developed several painful erythematous indurated patches at previous sampling sites and at the site where an arm board and adhesive tape were used in securing an intravenous infusion set. The lesions rapidly progressed to ulcers with central black eschars. Biopsies and cultures demonstrated a fungus, Aspergillus flavs, as the etiologic agent, without evidence of systemic dissemination. Local care, including s irgical debridement, were performed. The patient also received treatment with intravenous; amphotericin B followed by oral itraconazole. Six months later, the skin lesions had healed, leaving some scar and deformities.

Keyword

Itraconazole; Leukemia; Aspergillosis

MeSH Terms

Adhesives
Amphotericin B
Arm
Aspergillosis*
Aspergillus
Biopsy
Child*
Child, Preschool
Cicatrix
Congenital Abnormalities
Debridement
Drug Therapy
Fungi
Humans
Infusions, Intravenous
Itraconazole
Leukemia*
Male
Skin
Ulcer
Adhesives
Amphotericin B
Itraconazole
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