Korean J Dermatol.  1994 Jun;32(3):514-517.

A Case of Bowen' s Disease of the Nail Bed Presenting as Longitudinal Melanonychia

• Oh YS
• Hong JH
• Kye YC
• Oh CH

Abstract

Bowens disease is an intraepithelial squamous cell carcinoma. It occur s anywhere on the surface of the body. Bowens disease involving the nail bed epithelium is very rate. Recently, some literatures showed that human papillomavirus is sssociated with squamous cell carcinoma of the finger by in situ hybridization or polymerase chain reaction. A 30-year-old housewife deve]oped longitudinal melanonychia with as imptomatic fissured nail plate on her right third finger. The hiat,ologic specimen showed diffuse anaplastic change confined to the nail bed epithelium. The subungual eyithelium was found to contain human papillomavirus DNA type 31/33/35 with the use of in situ hybridization.

Keyword

Bowens disease; Nail bed; Longitudinal Melanonychia; Human papillomavirus; In Situ Hybridization

MeSH Terms

Adult
Bowen's Disease
Carcinoma, Squamous Cell
DNA
Epithelium
Fingers
Humans
In Situ Hybridization
Polymerase Chain Reaction
DNA