Korean J Dermatol.  1979 Dec;17(6):469-473.

A Case of Toxic Epiderma Nocrolysis

• Chae SM
• Kim JK
• Park JK

Abstract

Toxic epidermal necrolysis(T.E.N.) is a toxic erythema of the skin that undergoes epidermal necrolysis and peding so that it appears to have been scalded. There seem to be two basic form of T.E.N. In children, the deavage of the epidermis that results from an acantholytic-dyskeratotic cytolytic process is in the malpighian or granular layer and is usually induced by a staphylococci toxin. In adult, it is characterized by a full-thicknees cytolytic cleavage of skin above the basal layer and is usually precipitated by a drug. The authors observed a 17 year-old male with T.E.N. He began to notify the erythematous skin lesion with burning sensation on the whole body surface at 12 hours after oral administration of some drugs for common cold and developed the characteristic flaccid bullous and denuded lesions with tenderness within next 20 hours.

MeSH Terms

Administration, Oral
Adolescent
Adult
Burns
Child
Common Cold
Epidermis
Erythema
Humans
Male
Sensation
Skin