J Korean Ophthalmol Soc.  1968 Jun;9(2):7-12.

Electroretinogram in Experimental Ocular Siderosis

• Lee JH
• Youn WS

Abstract

Experimental ocular siderosis was induced in fourteen albino rabbits by the insertion of iron fragments through the scleral incision made at equatorial region. ERGs were recorded up to 30 days after the insertion of iron, both in scotopic and photopic conditions. Light stimulus used was electronic photoflash of 2 msec duration. The changes in the scotopic b-wave were classified into 3 types. The first type (4 eyes) showed gradual decrease finally attaining 54.6% of the original amplitude. The second type (3 eyes) showed supernormal b-wave during whole period of study, the increase reached 43.0% after 30 days. In the third type (6 eyes) the b-potential remained almost stationary. The scotopic a-wave changed in a similar way as the b-wave. Sometimes negative (-) type ERGs were recorded, especially during the falling stage of the b-potential. The photopic a- and b-waves changed almost parallel to the scotopic components. By slitlamp biomicroscopy and ophthalmoscopy, fibrous connective tissue proliferated around the iron fragments, never extending deep into the vitreous body. Fundi were well visible except the insertion site. Histological section revealed moderate scar tissue formation around the insertion site of iron, and mild visual cell and ganglion cell destructions.

MeSH Terms

Cicatrix
Connective Tissue
Ganglion Cysts
Iron
Ophthalmoscopy
Rabbits
Siderosis*
Vitreous Body
Iron