J Korean Pain Soc.  1989 May;2(1):61-65.

Clinical Experience of Pain Management of Lower Leg Pain due to Chloroma of Lumbosacral Bone in Chronic Myelogenous Leukemia

  • 1Department of Anesthesiology, Catholic University, Medical College, Seoul, Korea.


Chloroma is a localized myeloblastic tumor which may develop during the course of myelogenous leukemia or as a presenting sign of the disease. A 47-year-old female diagnosed as chronic myelogenous leukemia in her hematologic remission period complained of left lower leg pain. The lumbar-spine aeries showed multiple osteolytic changes in the left lateral border of the lumbar spine. An inhomogenous soft tissue mass involving left lateral aspects of lumbar vertebrae was identified by CT-scanning. At the first pain attack, lumbar epidural steroid and local anesthetic injection could abolish her pain and the patient could go a few days without pain. The following radiation therapy could also improve the symptom and retain the pain free interval. One month later, a second pain attack occurred and lumbar and caudal epidural steroid and local anesthetic injections could result only in an incidental relief of pain. Radiation and chemotherapy were started but failed to relieve pain. A neurolytic block was considered but the patients general condition was aggravated and even verbal communication with her became impossible.


Chloroma; Pain

MeSH Terms

Drug Therapy
Granulocyte Precursor Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*
Leukemia, Myeloid
Lumbar Vertebrae
Middle Aged
Pain Management*
Sarcoma, Myeloid*
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