Korean J Dermatol.  1973 Dec;11(3):187-192.

A Case of letterer-Siwe Disease

Abstract

Letterer-Siwe disease occurred in a 3 year 7 month old male child showing severe emaciation, hepatosplenomegaly, otitis media, hemorrhagic and impetiginous crusted patches on the body, and seborrheic dermatitis like skin rashes in the scalp. Also showed are severe anemia, thrombocytopenia, bronchopneumonia and multiple bony defects in skull. The child expired in a month after admission.


MeSH Terms

Anemia
Bronchopneumonia
Child
Dermatitis, Seborrheic
Emaciation
Exanthema
Histiocytosis, Langerhans-Cell*
Humans
Infant
Male
Otitis Media
Scalp
Skull
Thrombocytopenia
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