Korean J Dermatol.
1995 Oct;33(5):967-971.
A Case of Letterer-Siwe Dsease
Abstract
- Letterer-Siwe disease(LSD) is one of the Langerhans cell histiocytosis which includes Hand-Schuller-Christian disease and eosinophilic granuloma. We report a 1 year old girl with hepatosplenomegaly, lymphadenopathy, renal involvement, greasy scaly papules on the scalp and petechiae on the trunk which was diagnosed as LSD showing Langerhans granules in the electron microscopic examination.