J Korean Neurol Assoc.  2005 Jun;23(3):392-395.

Multiphasic Disseminated Encephalomyelitis (MDEM): Report of 3 Cases

Affiliations
  • 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. sunwooin@yumc.yonsei.ac.kr
  • 2Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.

Abstract

We report 3 cases of recurrent acute disseminated encephalomyelitis (ADEM) known as multiphasic disseminated encephalomyelitis (MDEM). The 3 cases presented with fever, headache, neck stiffness, abdominal pain, seizure and decreased mentality as well as focal neurologic deficits, which showed relatively good steroid responsiveness. Brain MRI revealed variable sized, multifocal, subcortical white matter lesions with gray matter involvement. The CSF study showed mild pleocytosis with negative oligoclonal band.

Keyword

Acute disseminated encephalomyelitis; Multiphasic disseminated encephalomyelitis

MeSH Terms

Abdominal Pain
Brain
Encephalomyelitis*
Encephalomyelitis, Acute Disseminated
Fever
Headache
Leukocytosis
Magnetic Resonance Imaging
Neck
Neurologic Manifestations
Seizures
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