Prevalence of Upper Gastrointestinal Lesions in Patients with or without Colon Polyp and Cancer

Shin, Woon Geon; Kim, Hak Yang; Heo, Pil Seog; Lee, Ja Young; Kim, Aukk; Kim, Jin Bong; Suh, Joong San; Lee, Jin Hyon; Kim, Jong Hyeok; Chang, Woong Ki; Kim, Dong Joon; Kim, Yong Bum; Park, Chong Kee; Yoo, Jae Young

Abstract

BACKGROUND/AIMS: It is unclear whether further evaluation for upper gastrointestinal tract is needed in the patients with colorectal lesions. We conducted this study to investigate the prevalence of simultaneous upper gastrointestinal lesion in the patients with colon cancer or polyp.
METHODS
Data of 904 consecutive patients who received both colonoscopic and gastroduodenoscopic examination from July 1997 to August 2000 were analyzed retrospectively. Gastroduodenal mucosal lesions such as gastric ulcer, duodenal ulcer, gastric polyp or gastric cancer were classified as clinically significant lesions. We compared the prevalence of upper gastrointestinal mucosal lesions between the patients with and without colonic lesions.
RESULTS
Fifty-five (25.9%) of 212 patients with colonic lesions and 87 (12.6%) of 692 patients without colonic lesions had simultaneous gastroduodenal lesions. The patients with colonic polyp or cancer had more gastroduodenal lesions than those without colonic lesions (p < 0.05). According to histologic finding of colonic lesion, the prevalence of gastroduodenal lesions was higher in the patients with hyperplastic polyp (p < 0.05) and tubular adenoma (p < 0.05) than in the patients without colonic lesions.
CONCLUSIONS
It is suggested that many of the patients who have colonic hyperplastic polyp and tubular adenoma may have simultaneous colonic and gastroduodenal lesions. Therefore, upper gastrointestinal endoscopy should be performed in the patients with colon neoplasia.