Korean J Infect Dis.
1997 Jul;29(4):313-316.
A Case of Rubella Complicated with Hemolytic Anemia
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
Abstract
- Rubella is a viral disease usually characterized by a benign febrile exanthem, manifested with fever, posterior occipital lymphadenopathy and pinkish rash in children. Most cases are recovered without any sequelae. However, it may lead to serious cardiac and ocular congenital malformation and fetal death in pregnant woman. Additionally postnatal rubella can be unusually complicated by encephalitis, meningitis, thrombocytopenic purpura, pneumonia and multiple organ disorder. Especially, hemolytic anemia following postnatally acquired rubella is very rare. Of the world, only twenty cases were reported in Japan during rubella outbreak from 1975 to 1977, and majority were Coombs' positive cases. But no case was reported until now in Korea. Resurgence of rubella has been recognized among adolescents in Korea since 1995. We experienced an adolescent patient with Coombs'-negative hemolytic anemia following rubella infection who has recovered by conservative management. We report the case with a review of literatures.
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