Korean J Cytopathol.  1999 Dec;10(2):157-162.

Fine Needle Aspiration Cytology of Peripheral T Cell Lymphoma of the Lung: A Case Report

• Shin OR
• Jung ES
• Lee YS
• Kang CS
• Kim BK
• Shim SI

Abstract

Primary non-Hodgkin's lymphoma of the lung is rare among extranodal lymphomas. The most common form is low grade B-cell type originated from the mucosa-associated lymphoid tissue (MALT) of the lung and primary peripheral T cell lymphoma of the lung is extremely rare. We recently experienced a case of fine needle aspiration cytology of primary peripheral T cell lymphoma of the lung in a 39-year-old male patient. The cytologic smears revealed some sheets of reactive epithelial cells, epithelioid histiocytes, and numerous polymorphous population of lymphoid cells composed of small and intermediate sized lymphoid cells and mature lymphocytes. Lymphoid cells were slightly larger than normal mature lymphocytes and showed significant irregularity of nuclear membrane. The internal nuclear structure was marked by chromatin clumping, clear parachromatin areas, and inconspicuous nucleoli. Histopathologically, atypical small lymphocytes infiltrated in the interstitium and alveolar sac. By the immunohistochemical study and molecular biologic study of gene rearrangement, the T cell clonality of atypical lymphoid cells was confirmed.

Keyword

Peripheral T cell lymphoma; Lung; FNAC

MeSH Terms

Adult
B-Lymphocytes
Biopsy, Fine-Needle*
Chromatin
Epithelial Cells
Gene Rearrangement
Histiocytes
Humans
Lung*
Lymphocytes
Lymphoid Tissue
Lymphoma
Lymphoma, Non-Hodgkin
Lymphoma, T-Cell, Peripheral*
Male
Nuclear Envelope
Chromatin