Tuberc Respir Dis.  2013 Apr;74(4):187-190. 10.4046/trd.2013.74.4.187.

Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium lentiflavum in a Patient with Bronchiectasis

• Jeong BH
• Song JU
• Kim W
• Han SG
• Ko Y
• Song J
• Chang B
• Hong G
• Kim SY
• Choi GE
• Shin SJ
• Koh WJ

• KMID: 1495860
• DOI: http://doi.org/10.4046/trd.2013.74.4.187

Abstract

We report a rare case of lung disease caused by Mycobacterium lentiflavum in a previously healthy woman. A 54-year-old woman was referred to our hospital due to chronic cough and sputum. A computed tomography scan of the chest revealed bilateral bronchiectasis with bronchiolitis in the right middle lobe and the lingular division of the left upper lobe. Nontuberculous mycobacteria were isolated twice from three expectorated sputum specimens. All isolates were identified as M. lentiflavum by multilocus sequence analysis based on rpoB, hsp65, and 16S rRNA fragments. To the best of our knowledge, this is the first documented case of M. lentiflavum lung disease in an immunocompetent adult in Korea.

Keyword

Nontuberculous Mycobacteria; Bronchiectasis; Mycobacterium Infections, Nontuberculous

MeSH Terms

Adult
Bronchiectasis
Bronchiolitis
Cough
Female
Humans
Korea
Lung
Lung Diseases
Multilocus Sequence Typing
Mycobacterium
Mycobacterium Infections, Nontuberculous
Nontuberculous Mycobacteria
Sputum
Thorax

Figure

• 

  Figure 1 A 54-year-old woman with bronchiectasis and nontuberculous mycobacterial lung disease caused by Mycobacterium lentiflavum. (A) A chest radiography reveals bilateral multifocal tram-track signs (white arrows). (B) A transverse chest computed tomography (CT) scan (2.5-mm-section thickness) on the level with the right inferior pulmonary vein reveals bilateral bronchiectasis (black arrowheads) in the right middle lobe and the lingular segment of the left upper lobe. (C) A chest CT scan obtained on the level with the superior segmental bronchus of the left lower lobe reveals bilateral bronchiolitis in both lungs (white arrowheads).

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