J Korean Assoc Maxillofac Plast Reconstr Surg.  2008 Mar;30(2):150-157.

Histomorphometric evaluation of osteogenesis with brushite implant surfaces in dogs

• Moon CW
• Kim SG
• Kim HK
• Moon SY
• Lim SC
• Oh JS
• Baik SM

Abstract

This study evaluated the influence of smooth and brushite-coated implant surfaces in dogs. The first through fourth mandibular premolars were extracted from eight young adult dogs. Twelve weeks after extraction, implantation was performed at the extraction sites. In total, 40 implant fixtures were implanted in the dog mandibles. Twenty machined implants served as controls and twenty brushite-coated surfaces served as tests. Dogs were sacrificed 2 and 4 weeks after implantation. The hemi-mandibles were obtained and processed histologically to obtain non-decalcified sections. Longitudinal sections of each implant were made and analyzed using light microscopy. The overall implant success rate was 83.3%. Histomorphometrically, the experimental group had a better percentage of bone-implant contact than the control group (P<0.05) and there was a significant difference between the 2- and 4-week groups after implantation (P<0.05). Our results suggest that the implant surface morphology influences the increase in peri-implant osteogenesis in the early period of peri-implant healing.

Keyword

Osteogenesis; Implant surface; Dog

MeSH Terms

Animals
Bicuspid
Calcium Phosphates
Dogs
Humans
Light
Mandible
Microscopy
Osteogenesis
Young Adult
Calcium Phosphates