- MicroRNA-181a-5p Curbs Osteogenic Differentiation and Bone Formation Partially Through Impairing Runx1-Dependent Inhibition of AIF-1 Transcription
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Liu J, Chang X, Dong D
- KMID: 2539829
- Endocrinol Metab.
- 2023 Feb;38(1):156-173.
- doi: 10.3803/EnM.2022.1516
Background: Evidence has revealed the involvement of microRNAs (miRNAs) in modulating osteogenic differentiation, implying the promise of miRNA-based therapies for treating osteoporosis. This study investigated whether miR-181a-5p influences osteogenic differentiation... -
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- Combined Application of Dentin Noncollagenous Proteins and Odontogenic Biphasic Calcium Phosphate in Rabbit Maxillary Sinus Lifting
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Yang G, Liu X, Huang T, Ding R, Wang Y
- KMID: 2539235
- Tissue Eng Regen Med.
- 2023 Feb;20(1):93-109.
- doi: 10.1007/s13770-022-00502-z
BACKGROUND: Teeth can be used as a raw material for preparing bone substitutes due to their similar chemical composition to bone. The objective of our study was to evaluate the... -
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- Expression of RUNX2/LAPTM5 in the Induction of MC3T3-e1 Mineralization and Its Possible Relationship with Autophagy
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Xing L, Li Y, Li W, Liu R, Geng Y, Ma W, Qiao Y, Li J, Lv Y, Fang Y, Xu P
- KMID: 2536454
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1223-1235.
- doi: 10.1007/s13770-022-00477-x
BACKGROUND: The study aims to correlate osteogenesis with autophagy during the mineralization induction of MC3T3-e1 through exploring the expression of runt-related transcription factor 2 (RUNX2)/lysosomal-associated transmembrane protein 5 (LAMPT5). METHODS: The... -
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- The Combination of Platelet Rich Plasma Gel, Human Umbilical Mesenchymal Stem Cells and Nanohydroxyapatite/polyamide 66 Promotes Angiogenesis and Bone Regeneration in Large Bone Defect
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Liu W, Huang Y, Liu D, Zeng T, Wang J, Li A, Wang D, Wang X
- KMID: 2536461
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1321-1336.
- doi: 10.1007/s13770-022-00471-3
BACKGROUND: In the present study, a novel tissue engineering bone graft including platelet rich plasma gel (PRP gel), human umbilical mesenchymal stem cells (HUMSCs) and nanohydroxyapatite/polyamide 66 (nHA-PA66) was constructed.... -
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- Modulation of Osteogenic Differentiation of Adipose-Derived Stromal Cells by Co-Treatment with 3, 4’-Dihydroxyflavone, U0126, and N-Acetyl Cysteine
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Song K, Yang GM, Han J, Gil M, Dayem AA, Kim K, Lim KM, Kang GH, Kim S, Jang SB, Vellingiri B, Cho SG
- KMID: 2532407
- Int J Stem Cells.
- 2022 Aug;15(3):334-345.
- doi: 10.15283/ijsc22044
Background and Objectives: Flavonoids form the largest group of plant phenols and have various biological and pharma-cological activities. In this study, we investigated the effect of a flavonoid, 3, 4’-dihydroxyflavone... -
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- Enhanced Bone Regeneration by Bone Morphogenetic Protein-2 after Pretreatment with Low-Intensity Pulsed Ultrasound in Distraction Osteogenesis
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Han JJ, Yang HJ, Hwang SJ
- KMID: 2533922
- Tissue Eng Regen Med.
- 2022 Aug;19(4):871-886.
- doi: 10.1007/s13770-022-00457-1
BACKGROUND: Bone morphogenetic protein 2 (BMP-2) and low-intensity pulsed ultrasound (LIPUS) have been used to enhance bone healing in distraction osteogenesis (DO). The aim of this study was to assess... -
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- Benefits of lumican on human bone health: clinical evidence using bone marrow aspirates
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Lee YS, Park SJ, Lee JY, Choi E, Kim BJ
- KMID: 2531481
- Korean J Intern Med.
- 2022 Jul;37(4):821-829.
- doi: 10.3904/kjim.2022.015
Background/Aims: Lumican, a small leucine-rich proteoglycan, has shown osteoprotective effects by synchronously stimulating bone formation and suppressing bone resorption. To clarify the role of lumican in human bone metabolism, the... -
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- Effects of Induction Culture on Osteogenesis of Scaffold-Free Engineered Tissue for Bone Regeneration Applications
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Park HM, Kim SH, Choi BH, Park SH
- KMID: 2528134
- Tissue Eng Regen Med.
- 2022 Apr;19(2):417-429.
- doi: 10.1007/s13770-021-00418-0
BACKGROUND: Restoration of the bone defects caused by infection or disease remains a challenge in orthopedic surgery. In recent studies, scaffold-free engineered tissue with a self-secreted extracellular matrix has been... -
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- Genotype-phenotype correlations and long-term efficacy of pamidronate therapy in patients with osteogenesis imperfecta
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Choi Y, Hwang S, Kim GH, Lee BH, Yoo HW, Choi JH
- KMID: 2528194
- Ann Pediatr Endocrinol Metab.
- 2022 Mar;27(1):22-29.
- doi: 10.6065/apem.2142144.072
Purpose: Osteogenesis imperfecta (OI) is a rare bone fragility disorder caused by defects in type 1 collagen biosynthesis. This study investigated the genotype-phenotype correlations and the efficacy of pamidronate therapy... -
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- Clinical Outcomes of Distraction Osteogenesis in Fourth Brachymetatarsia
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Kang SW, Lee JY, Lee HJ, Lee JY
- KMID: 2525478
- J Korean Orthop Assoc.
- 2022 Feb;57(1):59-67.
- doi: 10.4055/jkoa.2022.57.1.59
Purpose: Brachymetatarsia is a relatively rare disease that is characterized by one or more metatarsals shorter than the adjacent metatarsal bones by 5 mm or more. Corrective treatment is done,... -
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- Does periosteum promote chondrogenesis? A comparison of free periosteal and perichondrial grafts in the regeneration of ear cartilage
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Yoo H, Yoon T, Bae HS, Kang MS, Kim BJ
- KMID: 2521541
- Arch Craniofac Surg.
- 2021 Oct;22(5):260-267.
- doi: 10.7181/acfs.2021.00423
Background: Elastic ear cartilage is a good source of tissue for support or augmentation in plastic and reconstructive surgery. However, the amount of ear cartilage is limited and excessive use... -
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- Familial Otosclerosis Associated with Osteogenesis Imperfecta: A Case Report
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Lee HN, Jeon HJ, Seo YJ
- KMID: 2521621
- J Audiol Otol.
- 2021 Oct;25(4):230-234.
- doi: 10.7874/jao.2021.00122
Otosclerosis, a hereditary disorder characterized by disordered resorption and deposition of bone, results in progressive hearing loss. Osteogenesis imperfecta (OI) is a genetic disorder characterized by recurrent fractures, blue sclera,... -
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- Time-Course Changes in Bone Metabolism Markers and Density in Patients with Osteoporosis Treated with Romosozumab: A Multicenter Retrospective Study
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Inage K, Orita S, Eguchi Y, Shiga Y, Koda M, Aoki Y, Kotani T, Akazawa T, Furuya T, Nakamura J, Takahashi H, Suzuki-Narita M, Maki S, Hagiwara S, Inoue M, Norimoto M, Kinoshita H, Sato T, Sato M, Enomoto K, Takaoka H, Mizuki N, Hozumi T, Tsuchiya R, Kim G, Otagiri T, Mukaihata T, Hishiya T, Ohtori S
- KMID: 2519361
- Yonsei Med J.
- 2021 Sep;62(9):829-835.
- doi: 10.3349/ymj.2021.62.9.829
Purpose: In this multicenter retrospective observational study, we examined the early effects of romosozumab in patients with severe osteoporosis in terms of time-course changes in bone metabolism marker, improvement in... -
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- Classification and surgical management of temporomandibular joint ankylosis: a review
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Upadya VH, Bhat HK, Rao BS, Reddy SG
- KMID: 2519821
- J Korean Assoc Oral Maxillofac Surg.
- 2021 Aug;47(4):239-248.
- doi: 10.5125/jkaoms.2021.47.4.239
The paper reviews various classifications and surgical techniques for the treatment of temporomandibular joint ankylosis. PubMed, EBSCO, Web of Science, and Google Scholar were searched using a combination of keywords.... -
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- Comparison of Bone Mineral Density and Markers of Bone Turnover in Osteoporotic Women after 6-Month Treatment with Alendronate or Bazedoxifene: A Randomized Controlled Trial
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Han HS, Cho SH, Park MS, Sung KH, Lee KM
- KMID: 2516595
- J Bone Metab.
- 2021 May;28(2):131-137.
- doi: 10.11005/jbm.2021.28.2.131
Background: In a randomized controlled trial, we compared the bone mineral densities (BMDs) and blood markers of bone turnover during short-term treatment of osteoporotic women with bisphosphonate alendronate or bazedoxifene,... -
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- Outcome analysis of biplanar mandibular distraction in adults
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Chattopadhyay D, Vathulya M, Jayaprakash PA, Kapoor A
- KMID: 2513729
- Arch Craniofac Surg.
- 2021 Feb;22(1):45-51.
- doi: 10.7181/acfs.2020.00535
Background: Mandibular deficiency leading to facial asymmetry causes cosmetic deformity as well as psychological stigma for the patient. Correction of these mandibular asymmetries is a major challenge. The study investigates... -
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- Management of Osteogenesis Imperfecta: A Multidisciplinary Comprehensive Approach
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Cho TJ, Ko JM, Kim H, Shin HI, Yoo WJ, Shin CH
- KMID: 2508770
- Clin Orthop Surg.
- 2020 Dec;12(4):417-429.
- doi: 10.4055/cios20060
Osteogenesis imperfecta (OI) is characterized by recurring fractures and limb and spine deformities. With the advent of medical therapeutics and the discovery of causative genes, as well as the introduction... -
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- Stem Cells for the Regeneration of Tendon and Ligament: A Perspective
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Im GI, Kim TK
- KMID: 2508907
- Int J Stem Cells.
- 2020 Nov;13(3):335-341.
- doi: 10.15283/ijsc20091
Tendons are structures that connect muscles to the bones in our body and transmit the force generated by contraction of the muscles to the bones. Ligaments are structures that connect... -
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- Phelligridin D maintains the function of periodontal ligament cells through autophagy in glucose-induced oxidative stress
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Kim JE, Kim TG, Lee YH, Yi HK
- KMID: 2511808
- J Periodontal Implant Sci.
- 2020 Oct;50(5):291-302.
- doi: 10.5051/jpis.1903560178
Purpose: The objective of this study was to investigate whether phelligridin D could reduce glucose-induced oxidative stress, attenuate the resulting inflammatory response, and restore the function of human periodontal ligament... -
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- Effects of poly (ethylene glycol-propylene glycol) copolymer on hemostasis and osteogenesis in a rat calvarial defect model
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Kim HE, Yoon HY, Kim EJ, Kim SJ
- KMID: 2507023
- Korean J Vet Res.
- 2020 Sep;60(3):145-153.
- doi: 10.14405/kjvr.2020.60.3.145
Abstract: This study aimed to evaluate the effects of a bioabsorbable bone hemostatic agent comprising poly (ethylene glycolpropylene glycol) copolymers (PEG-PPG) on hemostasis and osteogenesis. Bilateral 3 mm diameter calvarial... -
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