J Korean Epilepsy Soc.
2009 Jun;13(1):27-30.
A Case of Carbamazepine-Induced Peripheral Neuropathy
- Affiliations
-
- 1Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul, Korea.
- 2Department of Rehabilitation Medicine, Seoul National University Boramae Medical Center, Seoul, Korea. ideale@empal.com
Abstract
- Peripheral neuropathy is rarely caused by antiepileptic drugs andmost cases were reported about phenytoin. Here we report carbamazepine- induced peripheral neuropathy, which is a very rare condition and the pathogenesis is not well understood. A 19-year-old man presented with a several-year history of bilateral foot pain and pes planus. He had craniopharyngioma and underwent neurosurgery in 1997 and 2007. He had been prescribed by the general dose (600 mg/day) of carbamazepine since 1998 for the treatment of postoperative epilepsy. His muscle power was normal in all limbs and there were no abnormal sensory symptom and sign. Findings of electrodiagnostic studies were compatible with sensorimotor polyneuropathy with mixed axonotmesis and demyelination. His family history and genetic diagnosis excluded the possibility of hereditary neuropathy. After dose reduction of carbamazepine, his bilateral foot pain has been improved slowly. We report a case of carbamazepine-induced peripheral neuropathy.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus: A Case Report
- A Case of Carbamazepine-induced Pseudolymphoma Syndrome
- Treatment of peripheral neuropathy: a multidisciplinary approach is necessary
- Neurofibromatous Polyneuropathy
- Peripheral Neuropathy in Older Adults
