Korean J Obes.  2010 Mar;19(1):1-8.

Omega-3 Index as a Risk Factor for Cardiovascular Disease and Its Application to Korean Population

• Park Y

Abstract

Of all known dietary factors, long-chain omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) may be the most protective against death from cardiovascular disease. Evidence continues to accrue for benefits of omega-3 fatty acids in the prevention of coronary heart disease and stroke. Anti-arrhythmogenic, anti-inflammatory, anti-thrombotic and hypolipidemic effects of omega-3-fatty acids are emerging as the most likely explanation. New evidence has confirmed and refined the cardioprotective risk factor of Omega-3 Index, the only standardized blood test of omega-3 fatty acids measuring content of erythrocyte eicosapentaenoic and docosahexaenoic acids. Current evidence suggests that individuals with coronary artery disease may reduce their risk of sudden cardiac death by increasing their intake of long-chain omega-3 fatty acids by approximately 1 g per day and achieving a target range of 8-10% Omega-3 Index. However, target range of Omega-3 Index for Koreans may be higher than 10%.

Keyword

Cardiovascular disease; Docosahexaenoic acid; Eicosapentaenoic acid; Inflammation; Lipoprotein; Omega-3 Index; Platelet

MeSH Terms

Blood Platelets
Cardiovascular Diseases
Coronary Artery Disease
Coronary Disease
Death, Sudden, Cardiac
Docosahexaenoic Acids
Eicosapentaenoic Acid
Erythrocytes
Fatty Acids, Omega-3
Hematologic Tests
Inflammation
Lipoproteins
Risk Factors
Stroke
Docosahexaenoic Acids
Eicosapentaenoic Acid
Fatty Acids, Omega-3
Lipoproteins