J Korean Neurosurg Soc.  2010 Feb;47(2):128-133. 10.3340/jkns.2010.47.2.128.

The Variable Ellipsoid Modeling Technique as a Verification Method for the Treatment Planning System of Gamma Knife Radiosurgery

• Hur BI
• Choi BK
• Sung SK
• Cho WH
• Cha SH
• Choi CH

• KMID: 1453143
• DOI: http://doi.org/10.3340/jkns.2010.47.2.128

Abstract

OBJECTIVE
The secondary verification of Leksell Gamma Knife treatment planning system (LGP) (which is the primary verification system) is extremely important in order to minimize the risk of treatment errors. Although prior methods have been developed to verify maximum dose and treatment time, none have studied maximum dose coordinates and treatment volume.
METHODS
We simulated the skull shape as an ellipsoid with its center at the junction between the mammillary bodies and the brain stem. The radiation depths of the beamlets emitted from 201 collimators were calculated based on the relationship between this ellipsoid and a single beamlet expressed as a straight line. A computer program was coded to execute the algorithm. A database system was adopted to log the doses for 31x31x31 or 29,791 matrix points allowing for future queries to be made of the matrix of interest.
RESULTS
When we compared the parameters in seven patients, all parameters showed good correlation. The number of matrix points with a dose higher than 30% of the maximal dose was within +/- 2% of LGP. The 50% dose volume, which is generally the target volume, differs maximally by 4.2%. The difference of the maximal dose ranges from 0.7% to 7%.
CONCLUSION
Based on the results, the variable ellipsoid modeling technique or variable ellipsoid modeling technique (VEMT) can be a useful and independent tool to verify the important parameters of LGP and make up for LGP.

Keyword

Gamma knife radiosurgery; Treatment planning system; Quality assurance

MeSH Terms

Brain Stem
Enzyme Multiplied Immunoassay Technique
Humans
Mamillary Bodies
Radiosurgery
Skull
Software