Korean J Dermatol.
2011 May;49(5):473-476.
Lymphomatoid Papulosis with Pseudocarcinomatous Hyperplasia
- Affiliations
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- 1Department of Dermatology, Kosin University College of Medicine, Busan, Korea. ksderm77@unitel.co.kr
Abstract
- Lymphomatoid papulosis (LyP) is a chronic lymphoproliferative disorder characterized by the appearance of crops of papules, nodules, and sometimes large plaques at different stages of development. Pseudocarcinomatous hyperplasia (PCH) presents with extreme proliferation of the epidermis with downgrowth into the dermis, which histologically mimics the features of squamous cell carcinoma. However, squamous cells usually are well differentiated, and atypicalities, such as individual cell keratinization, nuclear hyperplasia, and hyperchromasia, are minimal or absent. PCH has rarely been reported in LyP. Here, we showed that PCH associated with LyP may closely resemble squamous cell carcinoma, thereby giving rise to wrong diagnosis and treatment.
