Korean J Vet Res.  2012 Jun;52(2):133-139.

Antimicrobial resistance and frequency of BlaTEM in Escherichia coli isolated from non-diarrheic and diarrheic piglets

• Byun JW
• Kim HY
• Jung BY
• Bae YC
• Lee WK

Abstract

Antimicrobial resistance is one of the most concerns in pig industry. Escherichia (E.) coli have been used for the indicator to monitor the antimicrobial resistance. In this study, 321 E. coli from diarrheic and non-diarrheic piglets were tested for antimicrobial resistance and frequency of Bla TEM. In non-diarrheic piglets, they were resistant to oxytetracycline (93%), streptomycin (92%) and sulfadiazine (90%) but susceptible to ceftiofur (99%), colistin (97%), and enrofloxacin (82%). The isolates from diarrheic piglets were resistant to enrofloxacin (72.9%), ceftiofur (17.6%), and colistin (11.3%), whereas the resistance was 1%, 18% and 3% in case of non-diarrheic piglets, respectively. The resistance for amoxicillin/clavulanic acid (54.1%) and ceftiofur (22%) was high in isolates from post-weaning piglets. The resistance for colistin was 15.2% in nursery piglets. Seventy-three percent of isolates from diarrheic piglets showed high multidrug resistance profile (more than 13 antimicrobials) compared to those from non-diarrheic pigs in which 71% of isolates showed moderate multidrug resistance profile (7 to 12 antimicrobials). The frequency of BlaTEM in E. coli from non-diarrheic and diarrheic piglets was 57% and 69%, respectively. The results might provide the basic knowledge to establish the strategies for treatment and reduce antibiotic resistance of E. coli in piglets.

Keyword

antimicrobial resistance; BlaTEM; diarrhea; E. coli; piglets

MeSH Terms

Cephalosporins
Colistin
Diarrhea
Drug Resistance, Microbial
Drug Resistance, Multiple
Escherichia
Escherichia coli
Fluoroquinolones
Nurseries
Organothiophosphorus Compounds
Oxytetracycline
Streptomycin
Sulfadiazine
Swine
Cephalosporins
Colistin
Fluoroquinolones
Organothiophosphorus Compounds
Oxytetracycline
Streptomycin
Sulfadiazine