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Treatment Outcomes after Discontinuation of Ethambutol due to Adverse Events in Mycobacterium avium Complex Lung Disease

Kwon YS, Kwon BS, Kim OH, Park YE, Shim TS, Chong YP, Jo KW

BACKGROUND: Long-term administration of ethambutol (EMB) for Mycobacterium avium complex lung disease (MAC-LD) sometimes leads to permanent discontinuation of EMB due to various adverse events. This study aimed to investigate...
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Evaluation of the QuantaMatrix Multiplexed Assay Platform for Molecular Diagnosis of Multidrug- and Extensively Drug-Resistant Tuberculosis Using Clinical Strains Isolated in Myanmar

Chang Y, Kim S, Kim Y, Ei PW, Hwang D, Lee J, Chang CL, Lee H

BACKGROUND: Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes...
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Diversity of Genetic Environment of bla(CTX-M) Genes and Antimicrobial Susceptibility in Extended-spectrum β-lactamase producing Escherichia coli Isolated in Korea

Yang YY, Suh MH

Increasing resistance due to the production of extended-spectrum β-lactamase (ESBL) in Escherichia coli is a major problem to public health and CTX-M enzymes have become the most prevalent ESBL worldwide....
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Management of Typhoid Fever – Clinical and Historical Perspectives in Korea

Chang MS, Woo JH, Kim S

Typhoid fever, showed a dramatic decrease in its incidence from 56 per 100,000 population just after Korea's independence to
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Prescription of Antibiotics for Adults with Acute Infectious Diarrhea in Korea: A Population-based Study

Lee HJ, Park KH, Park DA, Park J, Bang BW, Lee SS, Lee EJ, Kim YJ, Hong SK, Kim YR

BACKGROUND: Acute infectious diarrhea (AID) is a commonly observed condition globally. Several studies recommend against the use of empiric antibiotic therapy for AID, except in some cases of travelers' diarrhea....
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Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma pneumoniae pneumonia in children

Yang HJ

Although Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, the emergence of macrolide-resistant MPP (MRMP) has made its treatment challenging. MRMP rapidly spread after the 2000s, especially in...
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Pharmacokinetic and pharmacodynamic integration of enrofloxacin against Salmonella Enteritidis after administering to broiler chicken by per-oral and intravenous routes

Kang J, Hossain MA, Park HC, Kim Y, Lee KJ, Park SW

It is crucial to optimize the dose of fluoroquinolones to avoid antibiotic resistance and to attain clinical success. We undertook this study to optimize the dose of enrofloxacin against Salmonella...
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Antimicrobial resistance profiles of vancomycin-resistant Enterococcus species isolated from laboratory mice

Yamanaka H, Kadomatsu , Takagi T, Ohsawa M, Yamamoto N, Kubo N, Takemoto T, Ohsawa K

Isolates of 24 enterococci, 5 Enterococcus casseliflavus and 19 Enterococcus gallinarum, possessing vanC genes and showing low-level resistance to vancomycin were obtained from mice from commercial mouse breeding companies. Since...
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Delafloxacin, a New Miracle in Antibiotics Armamentarium for Bacterial Infections

Rahman MS, Koh YS

The persistent antibiotics resistant issue has emerged as an influencing factor to deteriorate community health. So, new antibiotics development is urgent for the treatment of bacterial infections. Alternatively, delafloxacin is...
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Trend of multidrug and fluoroquinolone resistance in Mycobacterium tuberculosis isolates from 2010 to 2014 in Korea: a multicenter study

Kim H, Mok JH, Kang B, Lee T, Lee HK, Jang HJ, Cho YJ, Jeon D

BACKGROUND/AIMS: This study was conducted to evaluate the recent prevalence and trend of anti-tuberculosis (TB) drug resistance with a focus on multidrug-resistance (MDR) and fluoroquinolone resistance in South Korea. METHODS: We...
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Analysis of Integrons and Antimicrobial Resistances of Multidrug Resistant Escherichia coli Isolated in Korea

Yang YY, Suh MH

Antibacterial drugs are one of the most important therapeutic agents of bacterial infections but multidrug resistant Escherichia coli (MDREC) is an increasing problem worldwide. Major resistance mechanism of MDREC is...
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Comparing infective complications from transrectal ultrasound guided prostate biopsy following transition to single dose oral ciprofloxacin prophylaxis

Farag M, Riddell S, Daffy J, Wong LM

PURPOSE: To examine the incidence of infective complications post Transrectal Ultrasound Guided Prostate Biopsy (TRUSPB), after transition to preoperative administration of single dose oral ciprofloxacin. MATERIALS AND METHODS: A retrospective study...
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach

Sood D, Kumar N, Singh A, Sakharkar , Tomar V, Chandra R

Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary...
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Clinical characteristics of postoperative febrile urinary tract infections after ureteroscopic lithotripsy

Kim JW, Lee YJ, Chung JW, Ha YS, Lee JN, Yoo ES, Kwon TG, Kim BS

PURPOSE: Ureteroscopic lithotripsy (URS) is gaining popularity for the management of ureteral stones and even renal stones, with high efficacy and minimal invasiveness. Although this procedure is known to be...
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Determining Genotypic Drug Resistance by Ion Semiconductor Sequencing With the Ion AmpliSeqâ„¢ TB Panel in Multidrug-Resistant Mycobacterium tuberculosis Isolates

Park J, Shin SY, Kim K, Park K, Shin S, Ihm C

BACKGROUND: We examined the feasibility of a full-length gene analysis for the drug resistance-related genes inhA, katG, rpoB, pncA, rpsL, embB, eis, and gyrA using ion semiconductor next-generation sequencing (NGS)...
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Clinical Aspects and Treatment Outcomes of Moraxella keratitis

Song YY, Bang S, Lee TE, Kang WS, You IC

PURPOSE: To analyze the clinical presentation, predisposing risk factors, and evaluate the treatment outcomes of Moraxella keratitis. METHODS: A retrospective analysis was conducted of 12 culture positive cases of Moraxella keratitis...
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Optimal Modified Extended Antibiotic Prophylaxis for Prostate Biopsy: The Addition of Two Intravenous Doses of Amikacin to Ciprofloxacin

Yu SH, Jung SI, Kim MS, Chung HS, Kwon DD

PURPOSE: This retrospective study was undertaken to investigate whether increasing amikacin dosage for ciprofloxacin prophylaxis in patients with fluoroquinolone (FQ)-resistant rectal flora reduce infectious complications after transrectal ultrasound-guided prostate biopsy...
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Prevalence of Fecal Carriage of CTX-M-15 Beta-Lactamase-Producing Escherichia coli in Healthy Children from a Rural Andean Village in Venezuela

Araque M, Labrador I

OBJECTIVES: Antimicrobial resistant extended-spectrum-β-lactamase-producing Enterobacteriaceae (ESBL-PE) have been shown to be present in healthy communities. This study examined healthy children from the rural Andean village of Llano del Hato, Mérida,...
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Antimicrobial Susceptibilities of Enterobacteriaceae in Community-Acquired Urinary Tract Infections during a 5-year Period: A Single Hospital Study in Korea

Park JJ, Seo YB, Lee J

BACKGROUND: Through investigating antimicrobial susceptibility patterns of Enterobacteriaceae in community-acquired urinary tract infection (CA-UTI), we provide basic evidence for the use of empirical antibiotics in CA-UTI. MATERIALS AND METHODS: We retrospectively...
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Levofloxacin-induced Fixed Drug Eruption: A Case Report

Han SS, Oh EH, Kwon HI, Ko JY, Ro YS, Kim JE

  • KMID: 2391167
  • Korean J Dermatol.
  • 2017 Aug;55(7):445-448.
Fixed drug eruptions (FDEs) are characterized by the presence of site-specific recurrence of a solitary or multiple, well-circumscribed, erythematous macules or patches that recur with each exposure to a particular...
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