J Korean Neurotraumatol Soc.  2009 Dec;5(2):53-56. 10.13004/jknts.2009.5.2.53.

The Relation between Recurrence and Antiplatelet or Anticoagulant Agents on Chronic Subdural Hemorrhage

Affiliations
  • 1Department of Neurosurgery, Seoul Veterans Hospital, Seoul, Korea. colloseum@freechal.com

Abstract


OBJECTIVE
The purpose of this study was to examine the corelation of the recurrence rate and the use of antiplatelet agent or anticoagulant agent on chronic subdural hematoma patient group, and to find the appropriate time that reuse the agents.
METHODS
Between January 2007 and December 2008, 37 patients has undergone burr hole trephination for chronic subdural hematoma. Among them, 8 patients had been used antiplatelet or anticoagulant agent (agent using group). The other patients were agent non-using group. We reviewed medical and laboratory records retrospectively.
RESULTS
Preoperative laboratory finding including prothrombin time (PT), activated partial thromboplastin time (aPTT), international normalized ratio (INR), bleeding time (BT) were all within normal range on agent using group. Follow up laboratory findings were also all within normal range. The recurrence rate on agent using group was not superior to agent non-using group (12.5% : 13.8%). The patients with heart problem were took medication again after drainage catheter removal (postoperative second or third day). The prescribed medicines were restarted to old cerebral infarction patients on postoperative seventh day.
CONCLUSION
The use of antiplatelet or anticoagulant agents are not influenced recurrence rate on chronic subdural hematoma operation if the patients have no bleeding tendency before operation. Re-administration of agents may be possible within postoperative seventh day.

Keyword

Chronic subdural hemorrhage; Antiplatelet agent; Anticoagulant agent; Recurrence

MeSH Terms

Anticoagulants
Bleeding Time
Catheters
Cerebral Infarction
Drainage
Follow-Up Studies
Heart
Hematoma, Subdural
Hematoma, Subdural, Chronic
Hemorrhage
Humans
International Normalized Ratio
Partial Thromboplastin Time
Prothrombin Time
Recurrence
Reference Values
Anticoagulants

Reference

1. European Atrial Fibrillation Trial Study Group. Secondary prevention in non-rheumatic atrial fibrillation and transient ischaemic attack or minor trauma. Lancet. 1993; 342:1255–1262.
2. Gallagher D. Current management of atrial fibrillation. Med Today. 2004; 5:41–51.
3. Gelabert-Gonzalez M, Iglesias-Pais M, Garcia-Allut A, Martinez-Rumbo R. Chronic subdural haematoma: surgical treatment and outcome in 1000 cases. Clin Neurol Neurosurg. 2005; 107:223–229.
4. Gonugunta V, Buxton N. Warfarin and chronic subdural haematomas. Br J Neurosurg. 2001; 15:514–517.
Article
5. Kiymaz N, Yilmaz N, Mumcu C. Controversies in chronic subdural hematoma: continuous drainage versus one-time drainage. Med Sci Monit. 2007; 13:CR240–CR243.
6. Mellergård P, Wisten O. Operations and re-operations for chronic subdural haematomas during a 25-year period in a well defined population. Acta Neurochir (Wien). 1996; 138:708–713.
7. Nakaguchi H, Tanishima T, Yoshimasu N. Factors in the natural history of chronic subdural hematomas that influence their postoperative recurrence. J Neurosurg. 2001; 95:256–262.
Article
8. Nakajima H, Yasui T, Nishikawa M, Kishi H, Kan M. The role of postoperative patient posture in the recurrence of chronic subdural hematoma: a prospective randomized trial. Surg Neurol. 2002; 58:385–387.
Article
9. O'Brien DF, Basu S, O'Donnell JR, Roberts GA, Phillips J. The impact of aspirin therapy and anticoagulation on the prevalence of spontaneous subdural hematoma. Ir Med J. 2000; 93:244–246.
10. Okada Y, Akai T, Okamoto K, Iida T, Takada H, Iizuka H. A comparative study of the treatment of chronic subdural hematoma-burr hole drainage versus burr hole irrigation. Surg Neurol. 2002; 57:405–409.
Article
11. Reymond MA, Marbet G, Radü EW, Gratzl O. Aspirin as a risk factor for hemorrhage in patients with head injuries. Neurosurg Rev. 1992; 15:21–25.
Article
12. Rust T, Kiemer N, Erasmus A. Chronic subdural haematomas and anticoagulation or anti-thrombotic therapy. J Clin Neurosci. 2006; 13:823–827.
Article
13. Tokmak M, Iplikcioglu AC, Bek S, Gökduman CA, Erdal M. The role of exudation in chronic subdural hematomas. J Neurosurg. 2007; 107:290–295.
Article
14. Torihashi K, Saamasa N, Yoshida K, Narumi O, Chin M, Yamagata S. Independent predictors for recurrence of chronic subdural hematoma: a review of 343 consecutive surgical cases. Neurosurgery. 2008; 63:1125–1129.
15. Yamamoto H, Hirashima Y, Hamada H, Hayashi N, Origasa H, Endo S. Independent predictors of recurrence of chronic subdural hematoma: results of multivariate analysis performed using a logistic regression model. J Neurosurg. 2003; 98:1217–1221.
Article
16. Zingale A, Chibbaro S, Florio A, Distefano G, Porcaro S. Management of chronic subdural hematoma in patients treated with anticoagulation. J Neurosurg Sci. 1999; 43:277–284.
Full Text Links
  • JKNTS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr