Res Vestib Sci.  2013 Jun;12(2):58-61.

Recurrent Vertigo in Vestibular Schwannoma Responsive to Oxcarbazepine

Affiliations
  • 1Department of Neurology, Pusan National University Yangsan Hospital, Yangsan, Korea.
  • 2Department of Neurology, Pusan National University Hospital, Busan, Korea. kdchoi@medimail.co.kr

Abstract

Vestibular schwannoma (VS) are benign neoplasms that arise from Schwann cells of the eighth cranial nerve. Although progressive unilateral hearing loss with dizziness or disequilibrium provides a high suspicion index of VS, vertigo is the symptom causing the most pronounced negative effect on quality of life in patients with VS. We report a 55-year-old woman with recurrent paroxysmal vertigo and hyperventilation-induced nystagmus due to VS, which improved by oxcarbazepine treatment. We suggest that episodic vertigo in VS may be ascribed to the ectopic paroxysmal neuronal discharge from the partially demyelinated vestibular nerve due to tumor compression.

Keyword

Acoustic neuroma; Episodic vertigo; Oxcarbazepine

MeSH Terms

Carbamazepine
Dizziness
Female
Hearing Loss, Unilateral
Humans
Neuroma, Acoustic
Neurons
Quality of Life
Schwann Cells
Vertigo
Vestibular Nerve
Vestibulocochlear Nerve
Carbamazepine
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