J Korean Med Sci.
1991 Mar;6(1):21-29. 10.3346/jkms.1991.6.1.21.
Assessment of regional cerebral blood flow (rCBF) in ischemic stroke using Tc-99m HMPAO SPECT: comparison with CT and MR findings
- Affiliations
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- 1Department of Neurology and Nuclear Medicine, College of Medicine, Seoul National University, Korea.
- KMID: 1421511
- DOI: http://doi.org/10.3346/jkms.1991.6.1.21
Abstract
- To assess the regional cerebral blood flow (rCBF) in ischemic stroke, we analyzed the findings of single photon emission computed tomography (SPECT) using technetium-99m hexamethyl propyleneamine oxime (Tc-99m HMPAO). The SPECT images revealed abnormal areas of decreased perfusion in 29 out of 31 subjects (93.5%), which represented a higher detection rate than those for CT and MR (89.5%, respectively). Also, the areas of decreased perfusion were frequently larger than the lesions on CT and MR. Areas of decreased perfusion remote from the CT/MR lesions were found in 10 patients, including 8 with crossed cerebellar diaschisis (CCD). Thus, studies of rCBF by Tc-99m HMPAO SPECT can be useful in the assessment of ischemic stroke.
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